Ferric sulfate hemostasis: effect on osseous wound healing. II. With curettage and irrigation.

Hemorrhage control is often a problem for the clinician during osseous surgery. Ferric sulfate is an effective hemostatic agent, but with prolonged application to an osseous defect can cause persistent inflammation and delayed healing. The purpose of this investigation was to evaluate the effectiveness of ferric sulfate as a hemostatic agent and to determine its effect on healing after thorough curettage and irrigation from osseous surgical wounds.

Low pH-dependent Sindbis virus-induced fusion of BHK cells: differences between strains correlate with amino acid changes in the E1 glycoprotein.

Expression of alphavirus glycoproteins on the surface of infected cells leads to cell fusion after exposure to acidic pH. Two strains of Sindbis virus, AR339 (SV) and neuroadapted Sindbis virus (NSV), which differ in virulence for weanling mice, were found to differ in pH-dependent fusion. BHK-21 cells infected with SV fused maximally after shifting to pH 5.

Dendritic alterations in rat isocortex within an iron-induced chronic epileptic focus.

Ferrous chloride was injected into the rat isocortex in 5-microliters volumes as an aqueous solution with a concentration of 100 mM. Bursts of epileptiform discharges were sustained throughout the 6 weeks of observation. Nissl and Golgi-Cox stains showed gliosis and neuronal loss within the injection site.

Misconceptions about dental treatment for patients with genetic disease.

It is the goal of this conference to define the role of dentistry to the interdisciplinary treatment of genetic diseases. Certainly, with the inclusion of dental disciplines in centers devoted to the diagnosis and treatment of genetic disease, the diagnosis and treatment of secondary craniofacial manifestation and the diagnosis and treatment of genetic disease primary to the craniofacial and oral complex will be greatly accelerated and the many misconceptions about dental treatment for patients with any genetic disease will be significantly reduced.