Long-term treatment of obese children and adolescents using a telemedicine support programme.

A total of 140 obese patients (mean age 14 years) participated in a structured treatment and teaching programme (STTP) in hospital, with the aim of weight reduction. At both the start and finish of the STTP, patients underwent clinical and psychological examination. During an average hospital stay of 35 days, their mean bodyweight decreased from 82.

Increased carotid intima-media thickness and associations with cardiovascular risk factors in obese and overweight children and adolescents.

Objective: Overweight and obesity in children and adolescents contribute to the development of overweight and obesity in adulthood and subsequent cardiovascular disease. It was the aim of the trial to assess vascular status and associations with cardiovascular risk factors.

Patients And Methods: Eighty-one overweight or obese children and adolescents (age 13.

Trends in the management of arterial hypertension in patients with type 1 and insulin-treated type 2 diabetes mellitus over a period of 10 years (1989/1990-1994/1995). Results of the JEVIN trial.

Unlabelled: For populations of patients with insulin-treated diabetes mellitus, information about the quality of blood pressure control, an independent risk factor for cardiovascular mortality and morbidity, is widely lacking. Hence, it was the goal of the trial to evaluate the prevalence of arterial hypertension, the quality of blood pressure control and changes in treatment modalities over a period of 10 years.

Patients And Methods: In 1989/1990, Jena's St.

Diabetes, insulin, and risk of cancer.

Up to now, the studies involving diabetes mellitus and malignancies show controversial results: Many of them have found incidences of malignancies that were comparable or even lower than those in nondiabetic subjects; others conclude that diabetes mellitus is linked to a higher incidence of malignancies and/or a predictor of mortality from cancer. Insulin and its precursors, pro- and pre-proinsulin, have been shown to have some homology to the insulin-like growth factors, but, moreover they have some affinity to bind at receptors of the tumor growth factor and some hybrids too. Hence, an association between diabetes mellitus, insulin, hyperinsulinaemia, and carcinogenesis appears plausible.

Overweight, obesity and elevated blood pressure in children and adolescents.

Objective: Since many years in adults associations between dyslipidaemia, increased insulin resistance, arterial hypertension and the risk for cardiovascular diseases have been recognized. It was the aim of the present trial to investigate these associations and interactions between height, weight, body-mass index and blood pressure values in overweight/obese and normal weight children and adolescents.

Patients And Methods: 172 children and adolescents (n = 86 with overweight and obesity, n = 86 controls) were studied.