Publications by authors named "W B Schwartz"
Article Synopsis
- Frailty and sarcopenia increase the risk of hospitalization and mortality in patients with end-stage liver disease, making it crucial to identify frail individuals during liver transplant evaluations.
- In a study of 426 liver transplant recipients, 31% were sarcopenic and 25% were considered frail based on the Liver Frailty Index (LFI), with those groups showing longer post-transplant hospital stays.
- While neither frailty nor sarcopenia significantly affected 1-year survival rates, the LFI score was linked to increased mortality, suggesting that physical frailty assessment is a better predictor of outcomes than muscle mass alone.
Acuity assessments are vital for timely interventions and fair resource allocation in critical care settings. Conventional acuity scoring systems heavily depend on subjective patient assessments, leaving room for implicit bias and errors. These assessments are often manual, time-consuming, intermittent, and challenging to interpret accurately, especially for healthcare providers.
View Article and Find Full Text PDFIntraorbital amphotericin B for mucormycosis in an Allo-HSCT recipient.
Bone Marrow Transplant
August 2024
Diurnal Pain Classification in Critically Ill Patients using Machine Learning on Accelerometry and Analgesic Data.
IEEE Int Conf Bioinform Biomed Workshops
December 2023
Quantifying pain in patients admitted to intensive care units (ICUs) is challenging due to the increased prevalence of communication barriers in this patient population. Previous research has posited a positive correlation between pain and physical activity in critically ill patients. In this study, we advance this hypothesis by building machine learning classifiers to examine the ability of accelerometer data collected from daily wearables to predict self-reported pain levels experienced by patients in the ICU.
View Article and Find Full Text PDFArticle Synopsis
- The circadian clock is a system that helps regulate biological processes in a roughly 24-hour cycle, primarily influenced by light and other environmental cues.
- In mammals, the suprachiasmatic nucleus (SCN) in the brain acts as the central clock, coordinating the timing of various peripheral clocks in the body for better control of behavior, metabolism, and physiology.
- The study investigates how quickly these clocks adjust to sudden changes in the light-dark cycle, finding that arginine vasopressin pathways are crucial for maintaining clock stability both in the SCN and the anterior pituitary gland.