Publications by authors named "W B Collier"

Pests and diseases have caused significant problems since the domestication of crops, resulting in economic loss and hunger. To overcome these problems, synthetic pesticides were developed to control pests; however, there are significant detrimental side effects of synthetic pesticides on the environment and human health. There is an urgent need to develop safer and more sustainable pesticides.

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Energy systems modelling plays a pivotal role in understanding and optimizing complex energy systems. By integrating various factors such as energy demand, supply, infrastructure, and environmental considerations, energy systems modelling provides valuable insights for policymakers, industry stakeholders, and researchers. This can be key to informing stakeholder and policy decisions and facilitate the mobilisation of capital and market development to support the development of the energy sector.

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Article Synopsis
  • The ACCL0431 trial showed that sodium thiosulfate (STS) effectively reduces cisplatin-induced hearing loss in young patients aged 1-18.
  • A secondary analysis revealed that the incidence of hearing loss was significantly lower in those receiving STS (22.4%) compared to those who were only observed (54.0%).
  • The best protective effects of STS were seen in younger children (under 5 years) and those with specific cancers like neuroblastoma, indicating the need for tailored treatment strategies based on patient characteristics.
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Background: Interventions to increase physical activity are needed in adolescent and young adult survivors of childhood cancer who are largely inactive but at lifelong elevated risk of multiple chronic conditions improved by physical activity. The goals of the StepByStep study are to evaluate the effects of a 48-week distance-based, multi-component mobile health and social media behavioral intervention on physical activity, biomarkers of cardiometabolic health, and health-related quality of life.

Methods: This ongoing study is a two-arm, prospective, multi-site randomized controlled trial.

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We hypothesized that the inferior disease-free survival (DFS) seen in older patients who underwent αβ-T-cell/CD19-depleted (AB-TCD) haploidentical hematopoietic cell transplantation (HCT) for hematologic malignancies is caused by excessive exposure to rabbit antithymocyte globulin (rATG; Thymoglobulin). Between 2015 and 2023, 163 patients with a median age of 13 years (range, 0.4-27.

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