Publications by authors named "W B Bradford"
Article Synopsis
- * Despite concerns about safety and effectiveness, a study involving 42 patients showed that high use of telehealth did not lead to worse health outcomes for those with opioid use disorder.
- * The findings suggest that while telehealth makes care more accessible, it does not negatively impact the effectiveness of treatments for HIV and opioid dependence.
Background: Physician use of stigmatizing language in the clinical documentation of hospitalized adults with opioid use is common. However, patient factors associated with stigmatizing language in this setting remain poorly characterized.
Objective: This study aimed to determine whether specific demographic factors and clinical outcomes are associated with the presence of stigmatizing language by physicians in the clinical documentation of encounters with opioid-related ICD-10 (International Statistical Classification of Diseases, Tenth Revision) codes.
Importance: Mental health disorders are prevalent yet undertreated health conditions in the US. Given perceptions about the potential effect of cannabis on individuals with mental health disorders, there is a need to understand the association of cannabis laws with psychotropic use.
Objective: To investigate the association of medical and recreational cannabis laws and dispensary openings with the dispensing of psychotropic medications used to treat mental health disorders in the US.
Article Synopsis
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a serious genetic heart condition linked to dangerous heart rhythms, primarily caused by mutations in the PKP2 gene, with no current effective treatments available.
- Researchers developed a mouse model with a specific PKP2 mutation that mimics ARVC symptoms, leading to sudden death at a young age.
- Treatment with AAV-PKP2 gene therapy in these mice significantly restored normal PKP2 levels, preventing heart damage and improving survival rates, suggesting a potential new therapy for ARVC related to PKP2 mutations, especially those affecting RNA splicing.
Objective: The chronic impact of acetylcholinesterase inhibitors and other toxicants on Gulf War (GW) veterans' health symptoms is unclear.
Methods: Building on reports of adverse neuropsychological outcomes in GW pesticide applicators exposed to pesticides and pyridostigmine bromide, we now report on health symptoms in this group.
Results: In adjusted analyses, applicators with high exposures/impact to pesticides reported significantly more symptoms (18/34 symptoms) than applicators with lower exposures/impact and were more likely to meet modified Kansas and CDC Gulf War Illness criteria.