Publications by authors named "W B Alshuaib"

Parkinson's disease (PD) is a severe incurable neurological disorder. It is mostly characterized by non-motor symptoms like fatigue, dementia, anxiety, speech and communication problems, depression, and so on. Electroencephalography (EEG) play a key role in the detection of the true emotional state of a person.

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This study examined the effect of H2O2 on the delayed rectifier potassium current (IKDR) in isolated hippocampal neurons. Whole-cell voltage-clamp experiments were performed on freshly dissociated hippocampal CA1 neurons of SD rats before and after treatment with H2O2. To reveal the mechanism behind H2O2-induced changes in IKDR, cells were treated with different oxidizing and reducing agents.

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Purpose: Hearing level in some children may be abnormal due to conductive or sensorineural causes. In Kuwait, the hearing screening test is not conducted for newborns at public hospitals. We evaluated the hearing level of 159 Kuwaiti school children (age 6-12 years) at the Audiology Clinic of Ahmadi hospital to determine the extent and causes of hearing loss in these children.

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Newborn hearing screening in Kuwait.

Electromyogr Clin Neurophysiol

September 2007

Objectives: The purpose of the study was to detect permanent hearing loss in a universal newborn hearing screening (UNHS) program that included 200 normal ("well baby") newborn children and 15 children at high risk for hearing loss at Ahmadi Hospital in Kuwait.

Patients And Methods: Distortion product oto-acoustic emissions (DPOAEs) were conducted in the ward on newborns at the age of 2 days. Newborns who did not pass the DPOAE the second time (at the age of 1 month) were evaluated by a brainstem evoked response audiometry (BERA) test within the age of 3 months.

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We investigated the effects of H(2)O(2)-induced oxidative stress on the delayed-rectifier current (IK(DR)), neuronal physiological and morphological properties. Measurements were obtained from hippocampal CA1 neurons in control solution and from the same neurons after exposure to oxidative stress (short- and long-term H(2)O(2) external applications at 0.1, 1, and 10 mM).

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