Publications by authors named "W Ashley"

Platelet-fibrin clot formation is a key process in acute arterial thrombosis. The relationship between thrombin-induced platelet-fibrin clot strength (P-FCS) and fibrinogen levels in patients with cardiovascular disease (CVD) and COVID-19 has not been studied. In thhe current study, the contribution of fibrinogen to P-FCS has been explored in healthy subjects (n=157), patients hospitalized with COVID-19 (n=116), and patients with CVD (n=93) using thrombelastography (TEG 6s) with citrate cartridge.

View Article and Find Full Text PDF
Article Synopsis
  • Pregnancy is a recognized risk factor for Pituitary Apoplexy (PA), but non-gestational risk factors are inconsistent in existing research.
  • A systematic review of seven studies with nearly 5,000 participants revealed that about 10% experienced PA, with macroadenomas being a significant risk factor.
  • The study concludes that no single non-gestational risk factor solely causes PA, but larger tumor size and non-functioning adenomas are important factors, suggesting these patients may need prompt surgical intervention.
View Article and Find Full Text PDF

Objective: Neurosurgery has remained relatively homogeneous in terms of racial and gender diversity, trailing behind national demographics. Less than 5% of practicing neurosurgeons in the United States identify as Black/African American (AA). Research and academic productivity are highly emphasized within the field and are crucial for career advancement at academic institutions.

View Article and Find Full Text PDF

Introduction: Prasugrel, a potent P2Y receptor inhibitor, is not currently recommended in patients with stroke due to a higher rate of recurrent stroke. Prasugrel was associated with comparable efficacy to clopidogrel in reducing the risk of ischemic stroke in a recent phase III study.

Areas Covered: The authors provide an overview of the potential role of prasugrel in the management of ischemic stroke.

View Article and Find Full Text PDF

Objective: Over the past 20 years, female representation in neurosurgical residency programs has steadily increased. Still, the number of Black women and Black neurosurgical residents overall has remained stagnant. The authors aimed to understand the factors that led to this stagnation and how online public domain representation informs current and upcoming resident recruitment and decision-making.

View Article and Find Full Text PDF