Publications by authors named "W Amselgruber"

Article Synopsis
  • * Recent research focused on the expression of ZnT8 in the porcine gastrointestinal tract, particularly its relationship with hormones that regulate gut movements, revealing it co-localizes with hormones like ghrelin and motilin.
  • * The study highlights ZnT8's specific expression in certain endocrine cells related to gut motility, suggesting potential avenues for research into gastrointestinal issues commonly seen in type 1 diabetes patients.
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Objective: This study described corneal morphology in different domestic animals using histological and immunohistochemical methods. Specifically, we evaluated the species-specific distribution pattern of cytokeratins (CKs) and aquaporins (AQPs) to assess their contribution to the strength and transparency of the cornea, respectively.

Procedures: Corneal sections (2 μm thick) were obtained from 28 pigs, 11 cows, two goats, six horses, four dogs, and five cats and stained with hematoxylin-eosin and periodic acid-Schiff (PAS) reaction.

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A 3.5-year-old male Labrador retriever dog showed a short history of illness characterized by vomiting, apathy, and fever. Ultrasonographically, large nodular liver masses of high echogenicity were noted in both left and right liver lobes.

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Diabetes represents a major endemic disease throughout the world, and different therapeutic methods are used to treat the disease. Xenotransplantation of pig islet cells is a potential treatment for type 1 diabetes, but studies of protein expression in distinct islet cells are rare. ZnT8, a member of the slc30A gene family, is involved in islet endocrine hormone release and is a diabetes auto-antigen, raising the question of whether ZnT8 expression is regulated similarly in pig and human pancreas.

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Hemotrophic mycoplasmas (HM) are highly specialized red blood cell parasites that cause infectious anemia in a variety of mammals, including humans. To date, no in vitro cultivation systems for HM have been available, resulting in relatively little information about the pathogenesis of HM infection. In pigs, Mycoplasma suis-induced infectious anemia is associated with hemorrhagic diathesis, and coagulation dysfunction.

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