Adverse effects of environmentally relevant microplastics on in vivo endpoints, oxidative stress, and mitogen-activated protein kinase signaling pathway and multixenobiotic resistance system in the marine rotifer Brachionus plicatilis.

This study compared the toxicological effects of environmentally relevant microplastics (MPs) on the marine rotifer Brachionus plicatilis, focusing on MPs derived from various sources, including fossil fuel-based low-density polyethylene, bio-based polylactic acid (PLA), biodegradable poly(butylene adipate-co-terephthalate), and a novel PLA modified with β-cyclodextrin. We assessed in vivo effects such as reproductive output and mortality, alongside in vitro oxidative stress responses, including oxidative stress, antioxidant enzyme activities, and activation of the mitogen-activated protein kinase (MAPK) signaling pathway and the multixenobiotic resistance (MXR) system. Reproductive output and lifespan reduced significantly across all MP types, ranging from 0.

Dietary inclusion of black soldier fly (Hermetia illucens) larvae meal, with exogenous protease supplementation, in practical diets for striped catfish (Pangasius hypophthalmus, Sauvage 1878).

Fishmeal (FM) is a key component of commercial fish feeds, but due its unsustainable supply, the search for quality alternatives of FM has become a significant area of investigation worldwide. The insect-based proteins such as black soldier fly larvae (BSFL) are being recognized as an alternative ingredient. However, anti-nutritional factors in these alternatives may negatively affect nutrient utilization in fish.

Enhancing Cancerous Gene Selection and Classification for High-Dimensional Microarray Data Using a Novel Hybrid Filter and Differential Evolutionary Feature Selection.

Background: In recent years, microarray datasets have been used to store information about human genes and methods used to express the genes in order to successfully diagnose cancer disease in the early stages. However, most of the microarray datasets typically contain thousands of redundant, irrelevant, and noisy genes, which raises a great challenge for effectively applying the machine learning algorithms to these high-dimensional microarray datasets.

Methods: To address this challenge, this paper introduces a proposed hybrid filter and differential evolution-based feature selection to choose only the most influential genes or features of high-dimensional microarray datasets to improve cancer diagnoses and classification.

BCG's role in strengthening immune responses: Implications for tuberculosis and comorbid diseases.

The BCG vaccine represents a significant milestone in the prevention of tuberculosis (TB), particularly in children. Researchers have been developing recombinant BCG (rBCG) variants that can trigger lasting memory responses, thereby enhancing protection against TB in adults. The breakdown of immune surveillance is a key link between TB and other communicable and non-communicable diseases.

Plasmon-Enhanced Optoelectronic Graded Neurons for Dual-Waveband Image Fusion and Motion Perception.

Motion recognition based on vision detectors requires the synchronous encoding and processing of temporal and spatial information in wide wavebands. Here, the dual-waveband sensitive optoelectronic synapses performing as graded neurons are reported for high-accuracy motion recognition and perception. Wedge-shaped nanostructures are designed and fabricated on molybdenum disulfide (MoS) monolayers, leading to plasmon-enhanced wideband absorption across the visible to near-infrared spectral range.