Publications by authors named "W Alastair McLeod"

Article Synopsis
  • Systematic reviews on health equity often overlook differences in effectiveness across various equity factors, which hinders policy decisions.
  • A comprehensive search was conducted in multiple databases to identify studies that examine the methods used in systematic reviews for assessing health inequalities.
  • Health inequalities are defined as unfair differences in health outcomes related to social factors, and the study focused on analyzing these differences based on the PROGRESS-Plus framework, which includes various social determinants of health.
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Background: Marine holobionts depend on microbial members for health and nutrient cycling. This is particularly evident in cnidarian-algae symbioses that facilitate energy and nutrient acquisition. However, this partnership is highly sensitive to environmental change-including eutrophication-that causes dysbiosis and contributes to global coral reef decline.

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Purpose: The purpose of the study was to investigate factors associated with early discontinuation of low-dose ketamine infusions due to adverse drug events (ADEs).

Methods: A retrospective, matched case-control study of surgical patients who received low-dose ketamine infusions for postoperative pain over 6 years was conducted. Forty-seven study patients, who required early discontinuation of their infusion due to ADEs, were included and matched 1:1 with 47 controls, who did not experience ADEs, for a total of 94 patients.

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We review the development of a disaster health care response system in Mississippi aimed at improving disaster response efforts. Large-scale disasters generate many injured and ill patients, which causes a significant utilization of emergency health care services and often requires external support to meet clinical needs. Disaster health care services require a solid infrastructure of coordination and collaboration to be effective.

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While topical thrombin application can markedly improve surgical hemostasis, rapid absorption of thrombin can result in pulmonary embolism and death. We report a case of accidental interstitial infiltration of topical thrombin after hemorrhoidectomy that was treated with administration of human antithrombin and heparin anticoagulation. Except for a marked decrease in antithrombin activity from super normal to normal values, the patient exhibited no laboratory or clinical signs of pulmonary embolism, thrombin mediated consumptive loss of procoagulants, or regional thrombosis.

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