Publications by authors named "W A Myers"

Hypoxia inducible transcription factors (HIFs) mediate the hypoxic response in metazoans. When sufficient O is present, Fe(II)/2-oxoglutarate (2OG)-dependent oxygenases (human PHD1-3) promote HIFα degradation via prolyl-hydroxylation. We report crystallographic, spectroscopic, and biochemical characterization of stable and inactive PHD2.

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Article Synopsis
  • - The study analyzed 21 youthful parricide offenders (ages 11-21) to explore links between mental health issues, psychopathy levels, and specific behaviors related to how they handled their victims' bodies after committing murder, focusing on "body movement" and "body alteration."
  • - One interesting finding was that one-third of the offenders engaged in "undoing" behaviors, motivated by psychological needs rather than practical reasons, yet those with a history of child abuse didn't show more of these behaviors compared to non-abused youth; many had high psychopathy levels.
  • - The research also noted that none of the youth with psychotic symptoms exhibited body management behaviors, and there was a clear distinction between how they and their non
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Article Synopsis
  • A 41-year-old male hiker experienced a serious medical emergency after consuming too much water while hiking in the Grand Canyon during hot weather, leading to multiple health issues.
  • He suffered from exercise-associated hyponatremic encephalopathy (EAHE), exertional rhabdomyolysis (ER), and acute kidney injury (AKI), which resulted in severe pain, disorientation, and a grand mal seizure during helicopter evacuation.
  • The case highlights the dangers of excessive water intake, potential complications from strenuous exercise, and the need for prompt treatment of life-threatening conditions like EAHE and compartment syndromes.
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