Publications by authors named "W A Joyce"
Article Synopsis
- - Cardiac phenotypic plasticity refers to the heart's ability to change its structure and function in response to ongoing stress or stimuli, which can be either beneficial or harmful.
- - The article discusses key components of cardiac plasticity, such as changes in heart structure, how the heart's muscle cells interact, and metabolic adjustments, emphasizing the molecular mechanisms behind these changes.
- - Future research combining -omics technologies with comparative physiology is expected to reveal more about the variability of cardiac function across different animal species.
Article Synopsis
- Mammalian cardiac troponin I (cTnI) has an amino-terminal extension with serine targets that get phosphorylated to improve heart relaxation during increased heart activity.
- Researchers found that some species like shrews and moles evolved to mimic this phosphorylation process, allowing them to maintain extremely high resting heart rates.
- The study suggests that humans could improve heart function in heart failure by considering the removal of a weakly spliced exon found in cTnI, which has implications for heart health.
Unlabelled: The early evolution of Pan-Chelonioidea (sea turtles) is poorly understood. This is in part due to the rarity of undeformed skulls of definitive early stem chelonioids. In this work, we redescribe the holotype of using µCT scans and segmentations of the skull.
View Article and Find Full Text PDFEditorial: Common methodological issues in comparative biochemistry and physiology.
Comp Biochem Physiol A Mol Integr Physiol
October 2024
Article Synopsis
- "Unlabelled" is a poorly understood mid Paleocene softshell turtle from North America, previously only known from postcranial remains, and recently described with new material from North Dakota that includes shells and cranial parts.
- The study shows that while shell variations challenge earlier classifications, the turtle still remains distinct from other species, supporting its unique placement in evolutionary trees based on new micro-CT analyses.
- Additionally, the findings suggest this turtle lived in aquatic environments, as indicated by the discovery of multiple individuals in a claystone deposit, hinting at a diet suited for crushing hard food items.