Publications by authors named "W A Christopherson"

► Most solitary fibrous tumors (SFTs) are benign tumors, but some behave more aggressively. ► Correlation between pathologic grading and clinical behavior is poor but immunohistochemical profiles may be of use. ► Most disease is limited to site of origin, but complete surgical resection with follow-up is the standard of care.

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The study objective was to determine the effectiveness of a phenotypic chemoresponse assay in predicting response to chemotherapy measured by progression-free interval (PFI) in a retrospective series of ovarian cancer patients whose tumor specimens had been tested with the ChemoFx assay. A statistically significant correlation between assay prediction of response and PFI was observed in 256 cases with an exact or partial match between drug(s) assayed and received. In 135 cases with an exact match, the hazard ratio for progression of the resistant group was 2.

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Background: Uterine artery embolization is an increasingly popular alternative to hysterectomy or myomectomy for treatment of symptomatic uterine leiomyomata.

Case: A woman with a symptomatic uterine fibroid developed 2 areas of full-thickness necrosis on her right buttock following uterine artery embolization. After surgical debridement, healing occurred over 14 weeks.

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Objective: To measure the strength of the association between the factor V Leiden mutation and venous thromboembolism in gynecologic oncology patients.

Methods: We conducted a case-control study of gynecologic cancer patients in a referral center who were group matched for demographics, tumor type, and treatment. The prevalence of the factor V Leiden mutation was determined in both cases and controls, and an odds ratio was calculated.

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