Front Immunol
February 2022
Activated rheumatoid arthritis (RA) synovial fibroblasts (SFs) are among the most important cells promoting RA pathogenesis. They are considered active contributors to the initiation, progression, and perpetuation of the disease; therefore, early detection of RASF activation could advance contemporary diagnosis and adequate treatment of undifferentiated early inflammatory arthritis (EA). In this study, we investigated the expression of nucleotide-binding, oligomerization domain (NOD)-like receptor family, pyrin domain containing (NLRP)1, NLRP3 inflammasomes, Toll-like receptor (TLR)1, TLR2, TLR4, vitamin D receptor (VDR), and secretion of matrix metalloproteinases (MMPs) in SFs isolated from patients with RA, osteoarthritis (OA), EA, and control individuals (CN) after knee surgical intervention.
View Article and Find Full Text PDFAnn Hum Biol
December 2019
Facial anthropometric measurements in relation to self-esteem and self-perception have become a very popular topic, not only in anthropological and psychological research, but also in plastic reconstructive surgery. To compare the interrelations between facial perception, self-esteem and psychosocial well-being in patients after nasal surgery due to trauma, cancer and aesthetic needs. In total, ninety patients after nasal surgery (due to trauma, cancer and aesthetic reasons), and thirty control persons underwent facial anthropometry and answered questions related to facial perception (FP), self-esteem (SE) and psychosocial well-being (PW).
View Article and Find Full Text PDFKnee Surg Sports Traumatol Arthrosc
May 2018
Purpose: The objective of this study was to measure the diameters of 5- and 6-strand hamstring autografts and to evaluate the predictability of their thickness by other body size indices.
Methods: Data were collected from 122 skeletally mature adult patients, who had undergone arthroscopic anterior cruciate ligament reconstruction using only 5- or 6-strand hamstring autografts. The diameters of tibial and femoral ends of the grafts were measured with the precision of 0.