['Conditioning factor' in plant cell cultures of various taxa].

The activity of the "conditioning factor" from the cultures of plant cells of various taxa was assayed in biotests with the tobacco and wheat cell cultures. The conditioned media of crops did not activate the growth of a diluted (400-fold) culture of tobacco cells. Conditioned media from the cultures of cells of other monocotyledonous plants, such as asparagus or spiderwort, stimulated the tobacco culture growth like those from the cultures of cells of dicotyledonous and gymnospermous plants.

[Coimmobilization of proteolytic and bacteriolytic enzymes and properties of isolated materials].

Coimmobilization of proteolytic and bacteriolytic enzymes on a carboxyl-containing grafted cellulose copolymer was studied. The resistance of lysozyme to gamma-sterilization significantly increased after coimmobilization with a proteolytic enzyme. The resulting material accelerated the cleansing of wounds.

[The efficacy of replacement therapy in hypothyroidism].

The use of L-thyroxin in the substitution therapy for hypothyrosis is, in our judgement, a most pathogenetically well-grounded option. In the early period of the treatment of hypothyrosis with L-thyroxin the total clearance of thyroxin is accelerated and is in inverse relationship to the initial blood hormone level. From the results of pharmacokinetic studies a specific individualized regimen is proposed of thyroxin administration in the early period of the treatment of hypothyrosis, which allows the thyroxin concentrations to be achieved within the range of 120-150 micrograms.