The effect of body weight and psychological characteristics on periodontal disease development.

The aim of the study was to examine the association between periodontal health in young patients with various body mass indexes and psychological traits such as temperament, level of anxiety, and autonomic nervous system tone.

SYNCHRONOUS HAIRY CELL LEUKEMIA AND HEPATOCELLULAR CARCINOMA: A CASE REPORT.

Multiple primary malignant tumors are characterized by independent occurrence and development of two or more malignant neoplasms in the same patient. We present an extremely rare case of synchronous double primary malignancies, hairy cell leukemia and hepatocellular carcinoma with lethal outcome. Diagnosis of hepatocellular carcinoma was difficult due to the presence of lymphoproliferative disease, which complicated the visualization of the process using ultrasonography.

MINERALIZATION OF TEETH ENAMEL AFTER ERUPTION.

Objective: The aim: The paper was aimed at the study of the processes of mineralization of the enamel of the permanent tooth after its eruption.

Patients And Methods: Materials and methods: To study the structure of the enamel of permanent teeth has been carried out using light and electron microscopy. The study of the process of the development of the primordia of the permanent teeth involved 10 culled puppies of 30-40 days of age.

DENTAL CROWN BIOMINERALIZATION DURING ITS HISTOGENESIS.

Objective: The aim: Thepaper wasaimedat thestudyof thebiomineralization processesofa permanentdental crown in thepostnatal period of histogenesis.

Patients And Methods: Materials and methods: The study involved 30 culled puppies aged 30-40 days. To study the histogenesis of the germs of the permanent tooth from the cuticular epithelium in the postnatal period microscopic, electron microscopic, immunohistochemical methods of study have been used.

Clinicomorphological observation of refractory hepatoblastoma: a case report.

The clinical case of refractory hepatoblastoma with lethal outcome followed by pathomorphological verification has been analyzed. The true causes of hepatoblastoma development remain unknown. The prognostic factors of the disease require detailed study in complex investigations that would include histological, clinical, laboratory, and immunohistochemical characteristics.

The observation of congenital retroperitoneal large size neuroblastoma.

The article represents current literature data on epidemiological, clinical-morphological features and diagnostic criteria of neuroblastoma. The case of large congenital neuroblastoma with multiple metastases in the newborn child is presented. The histological picture and immunohistochemical profile of the tumor allowed us to consider this type of neuroblastoma as the least differentiated variant (subtype, "neuroblastoma rich in Schwann stroma"), with rapid progression and metastasizing started before the birth of the child.

Chronic systemic inflammation in the pathogenesis of comorbid pathology and it's correction.

Objective: Introduction: The paper presents the findings of our own study on the changes of the systemic inflammation in patients with type 2 diabetes mellitus (DM2) and ischemic heart disease (IHD) during the combination treatment with metformin and pioglitazone. The aim of the paper is to define the dynamics of the systemic inflammation in patients with type 2 diabetes mellitus and ischemic heart disease in combination treatment with metformin and pioglitazone.

Patients And Methods: Meterials and methods: 95 patients with IHD concomitant with DM2 have been treated.

Current view on the structure and function of the frontal sinus: literature review.

Objective: Introduction: Chronic inflammatory diseases of the mucous membranes of the nose, paranasal sinuses, and pharynx are the most common pathology of the upper airways. Pathological processes develop more often in the maxillary and ethmoidal sinuses than in the frontal ones; however, the clinical course of frontitis is more severe. Fundamental understanding of the specific structure of frontal sinuses is crucial in the awareness of the precursors of the onset and development of its pathology, the choice of methods of diagnostics and treatment.

The use of immunohistochemical methods in the study of morphofunctional features of the human paranasal sinuses: literature review.

Objective: Introduction:Chronic inflammatory diseases of the mucous membrane of the nose, paranasal sinuses, and pharynx are the most widespread pathology of the upper airways. The thorough study of the features of the organization of local immune protection of the mucous membrane of the paranasal sinuses is crucial for the deep understanding of the causes of the onset and development of this and other pathologies of the paranasal sinuses, the choice of methods of diagnostics and treatment. Consequently, immunohistochemical studies are of great potential and have become preferable for great number of researchers.

Stereomorphology of the glandular parenchyma of the inferoposterolateral area of human prostate gland.

Objective: Introduction: The human prostate gland contains numerous tubular masses of different calibers in its parenchyma. They form the tubuloalveolar prostate glandules, constituting from numerous prostatic excretory ductules as well as major excretory ducts. The aim: The study was aimed at 3D visualization of individual microelements of the tubuloalveolar aggregations, localized within the peripheral area.

Current studies of ukrainian researchers of stress impact on chest organs: literature review.

Objective: Introduction: Stress reactions allow the body to adapt to the various environmental factors using the universal complex of neurohumoral reactions. Excessive stress reduces adaptability of the body and can initiate the onset and development of various pathologies. In recent years, Ukrainian scientists have completed a series of studies on the analysis of various aspects of the stress effect on the body.

Morphological substantiation for acute immobilization stress-related disorders of adaptation mechanisms.

Introduction: Nowadays, an individual is being constantly accompanied by stresses in his/her everyday life. Stress reactions, produced in the process of evolution, have become the organisms' response to emergency action or pathological factors and are the important link in adaptation process. However, the adverse course of stress reaction can lead to derangement of the adaptation mechanisms in the body and become the element of the pathogenesis of various diseases.

[A case of primary diffuse large B-cell lymphoma of the brain].

The paper describes a case of primary extranodal diffuse large B-cell lymphoma of the cerebral hemispheres, which was regarded as an inflammatory disease of the brain during life and diagnosed only posthumously in the microscopically examination of the autopsy material by immunohistochemical studies.

The use of various models of chronic immobilization stress in experimental studies.

Introduction: Stress is defined as a complex of protective and disturbing responses of the organism, generated in the process of the evolution, which occur as a result of neuroendocrine and metabolic alterations in response to the impact of emergency or pathological factors. Hence, stress is an important link of the adaptive mechanism; however, its adverse course can contribute to pathogenesis of many diseases. The problem of stress, which has been under study for years, is still a relevant topic to be investigated.

Morphological and immunohistochemical characteristics of human trigeminal ganglion neurons in the prenatal period of development.

Introduction: Data related to the amount, size and morphological characteristics of cell elements of sensory ganglia at different stages of prenatal development has not been fully elucidated in recent scientific publications. At the same time publications considering the study of cell structure of trigeminal ganglion in the postnatal period confirm heterogeneity of its neurons. The aim of the research was to study morphological and immunohistochemical characteristics of human trigeminal ganglion neurons at 12-14 weeks of prenatal development.