Diagnosis of cystic fibrosis: a high heterogeneity of symptoms and genotypes in a Brazil population.

Introduction: In highly multiracial populations with inadequate newborn screening, knowledge of the various phenotypic presentations of Cystic Fibrosis (CF) can help reach an early diagnosis. This study aims to describe phenotypes and genotypes at the time of CF diagnosis in a state in the Northeast Region of Brazil.

Methods: Retrospective cross-sectional study.

Neuropathic pain in patients with sickle cell disease: a cross-sectional study assessing teens and young adults.

Chronic pain conditions are little studied and may be underestimated in sickle cell disease (SCD). The aim of this study was to identify the occurrence and characteristics of neuropathic pain (NP) in SCD patients. A sample of 56 patients was chosen from a total of 554 patients submitted to the inclusion criteria between 2015 and 2016.