Population Structure Based on Microsatellite Length Polymorphism, Antifungal Susceptibility Profile, and Enzymatic Activity of Clinical Isolates in Russia.

is an emerging multidrug-resistant fungal pathogen causing nosocomial transmission and invasive infections with high mortality. This study aimed to investigate the genetic relationships, enzymatic activities, and drug-resistance profiles of isolates to evaluate the population and epidemiological diversity of candidiasis in Russia. A total of 112 clinical isolates of were analyzed from May 2017 to March 2023 in 18 hospitals across Saint Petersburg, the Leningrad Region, and Moscow.

Genotyping of Russian isolates of fungal pathogen Trichophyton rubrum, based on simple sequence repeat and single nucleotide polymorphism.

Background: The Trichophyton rubrum species group consists of prevalent causative agents of human skin, nail and hair infections, including T rubrum sensu stricto and T violaceum, as well as other less well-established or debatable taxa like T soudanense, T kuryangei and T megninii. Our previous study provided limited evidence in favour of the existence of two genetic lineages in the Russian T rubrum sensu stricto population.

Objectives: We aimed to study the genetic structure of the Russian population of T rubrum and to identify factors shaping this structure.

[Functional hyperemia of the periodontium during the use of chewing gum].

Functional hyperemia developing in the periodontium after 30 sec chewing of a half of a standard chewing gum plate was studied by a noninvasive quantitative method. In subjects with clinically normal periodontium and normal tonic tension of the regional vessels the peak blood flow develops within the first minute of chewing and further vasomotions restore in 30 min. In changed vascular tone, particularly so in periodontal diseases, hyperemia develops persisting for at least 30 min.