Percutaneous direct endoscopic pancreatic necrosectomy.

Approximately 10%-20% of the cases of acute pancreatitis have acute necrotizing pancreatitis. The infection of pancreatic necrosis is typically associated with a prolonged course and poor prognosis. The multidisciplinary, minimally invasive "step-up" approach is the cornerstone of the management of infected pancreatic necrosis (IPN).

Gastric glomus tumor: A rare etiology of upper gastrointestinal bleed.

The glomus tumor of stomach is an unusual submucosal mesenchymal tumor of the gastrointestinal tract. We describe a 42-year-old female who presented with chronic anemia and an episode of painless hematemesis. A preoperative diagnosis of the probable gastric gastrointestinal stromal tumor was made.

Ectopic pancreas at the ampulla of Vater diagnosed with endoscopic snare papillectomy: A case report and review of literature.

Background: Ectopic pancreas is a rare developmental anomaly that results in a variety of clinical presentations. Patients with ectopic pancreas are mostly asymptomatic, and if symptomatic, symptoms are usually nonspecific and determined by the location of the lesion and the various complications arising from it. Ectopic pancreas at the ampulla of Vater (EPAV) is rare and typically diagnosed after highly morbid surgical procedures such as pancreaticoduodenectomy or ampullectomy.

A comparative observational study of early versus delayed feeding after percutaneous endoscopic gastrostomy.

Background: Percutaneous endoscopic gastrostomy (PEG) is the procedure of choice for long-term enteral feeding.

Objective: This prospective observational study was carried out to compare the safety of commencing feeding 3 h compared to 16-24 h after PEG tube placement.

Methods: One hundred and ten patients with oropharyngeal malignancies who had consented for PEG were enrolled.

FDG-PET and PET/CT in the clinical management of gastrointestinal stromal tumor.

The management of gastrointestinal stromal tumors (GISTs) has been revolutionized in recent years by two major developments: the introduction of imatinib mesylate as a targeted therapeutic agent and the dramatic change in the tumor metabolic activity following successful therapy making in fluorodeoxyglucose (FDG)-PET as the modality of choice for monitoring therapeutic response. In the present communication, we have explored the current role of PET/computed tomography (CT) imaging in GIST on the basis of a brief overview of the published studies and our experience on the subject gained in a large tertiary care setting. There is now convincing evidence that serial PET study is more sensitive and reliable for determining treatment response to imatinib mesylate in patients of GIST, when compared with only conventional CT monitoring.

Non-invasive detection of endothelial dysfunction in sickle cell disease by Doppler ultrasonography.

Objective: The purpose of the study was to assess endothelial function in sickle cell disease (SCD), to compare endothelial dysfunction between sickle cell anemia (SS) and sickle cell trait (SA) cases and to evaluate correlation of endothelial dysfunction with duration of symptoms and vaso-occlusive crises per year (voc/year) [severity of disease].

Methods: We investigated 37 steady state SCD cases, of which 19 were SS [mean age = 23.15 + 5.

Absolute coronary risk analyser--a tool for managing coronary heart disease risk.

Objectives: The aim of the present study was to develop a coronary risk analyser which can calculate authentically the absolute coronary risk of an individual for coronary risk management.

Methods And Results: After extensive literature survey was done to derive the most appropriate method to calculate the absolute coronary risk. Joint British recommendations derived from Framingham's heart study were adopted for its supreme sensitivity and specificity.

CORONARY RISK ANALYSIS - A STITCH IN TIME.

Coronary heart disease (CHD) is the major cause of sudden death amongst adults throughout the globe. Though the prevalence of CHD is increasing steadily all over, CHD amongst Indians is peculiar in the sense that it is more prevalent, more severe and appears at younger age. Development of CHD depends upon the status of various coronary risk factors in one's body.

AEROMEDICAL ASPECTS OF CONTACT LENSES (SOFT AND SEMISOFT).

A comprehensive clinical study on the effects of various aviation stresses on soft and semisoft contact lenses was carried out to find out their compatibility in aviation environment. Twenty subjects (11 aircrew and 9 non air-crew) participated in the study. Twelve of them were given soft lenses of water contents of 38%, 50% and 78% and rest 8 were given semisoft lenses of daily wear and extended wear type.