Publications by authors named "Vyacheslav Serpik"
Article Synopsis
- Phenylketonuria (PKU) is a genetic disorder that requires individuals to follow a strict low-phenylalanine diet for life to avoid serious neurological issues, but adhering to this diet can be difficult for patients and their families.
- A systematic review analyzed 49 studies to identify the various factors affecting adherence to this diet, categorizing them into family-related, patient-specific, environmental, and therapy-related factors.
- The review stresses the need for a comprehensive approach to support PKU patients, emphasizing that future research should focus on producing high-quality longitudinal and experimental studies for better insights.
Purpose: Stimulating cost reduction of pharmaceutical companies to optimize the structure of distribution of patients by the level of treatment costs in various programs.
Patients And Methods: In this article, we rise up the issues of pharmacoeconomic modeling related to the description of the patient flows in the pharmacoeconomic model and methods to determining the course dose of drugs under the restriction of integer computations. We established two possible ways of distributing patients through treatment regimens in pharmacoeconomic models, also analyzed the effects of simultaneous and uniform entry of patients into the model.