Exercise-induced changes in redox status of elite karate athletes.

Regular training has been claimed to increase the activity of antioxidant enzymes and, consequently, augments the resistance to oxidative stress; however, large volumes of training performed by elite sportsmen could lead to a chronic oxidative stress state. The aim of our study was to assess the oxidative status of elite athletes at the beginning of the preparatory and the beginning of the competition training phases, so that the influence of three months of programmed physical activity on redox status could be determined. The chronic effects of exercise on the redox state of the athletes were compared to the effects of a single bout of karate training.

Evaluation of myocardial relaxation in conditions of cardiac remodeling.

The term cardiodynamics refers to dynamic events associated with cardiac contraction and relaxation. The occurring wave of excitement spreads very quickly along the entire atrial musculature and after a brief AV retention it affects all muscle cells of the ventricles. Excitation, that is, the increase in action potentials, precedes the contraction of the myocardium, which follows the "all or none" rule.

[Oxidative status evaluation in elite karate athletes during training process].

Background/aim: Oxidative stress is a state of disturbed balance between reactive oxygen species (ROS) and reactive nitrogen species (RNS) on the one hand, and antioxidative defense on the other. As a result of oxidative stress we have irreversible changes in cell function leading to pathological tissue changes, development of many diseases and fast aging process. Increased consumption of oxygen during exercise could be the cause of oxidative stress.

[The use of combined hyperbaric oxygenation and erythropoietin in the treatment of cardiac insufficiency].

Introduction: The aim of this research is to evaluate therapy efficiacy of hyperbaric oxgenation (HBO) with regenerative effects on human tissues and erythropoietin, as a nonspecific growth factor.

Material And Methods: This study included a group of 9 patients with echocardiographically diagnosed cardiac insufficiency with ejection firaction (EF%) under 60%. HBO was used according to the protocol for patients with severe cardiac insufficiency (a total of 15 treatments).

[Effects of platelet single passage on coronary circulation in the isolated guinea-pig heart: focus on the L-arginine: nitric oxide system].

Introduction: In order to evaluate endothelial response to platelet single passage through coronary vascular bed, experiments on isolated guinea-pig hearts perfused by the Langendorff method at constant pressure were performed.

Material And Methods: Platelet single passage was performed with platelet-rich plasma obtained from healthy volunteers, as well as from patients with acute myocardial infarction. Hearts, isolated from guinea-pigs of either sex were perfused with Krebs-Hensenleit buffer.

Prostacyclin reduces incidence of myocardial damage after coronary endarterectomy.

Background: After coronary endarterectomy, patients have an increased incidence of perioperative myocardial infarction. This study was undertaken to evaluate the possible reduction of perioperative myocardial damage after coronary endarterectomy by intravenous utilization of prostacyclin.

Methods: Elective coronary artery bypass grafting was performed in 1,190 patients with diffuse and distal coronary artery disease, in whom endarterectomy of one or more vessels was used as a treatment.