Publications by authors named "Vui Thi Hoang"
Article Synopsis
- Scientists created new tools using special small proteins called peptides to find a malaria parasite better than current tests.
- They designed two peptides that can stick to the malaria parasite and tested them in different ways, finding that one was really good at detecting it.
- The new test methods showed they could spot the parasite much more effectively than regular tests, making it easier to track different types of malaria.
Article Synopsis
- Outbreaks of H5N2 avian influenza in South Korea have caused significant bird deaths, with recent surveillance revealing three specific isolates from wild birds that exhibit reassortment from various virus subtypes.
- These H5N2 viruses, while classified as low pathogenic, show genetic changes that could enhance virulence and adaptation to mammals, indicating a potential risk to animal and human health.
- The study underscores the importance of continuous monitoring of avian influenza in South Korea to address the threats posed by these evolving viruses.
Intervirology
January 2022
Article Synopsis
- The avian influenza virus is highly contagious in birds and occasionally affects humans, with variations in its genetic makeup necessitating ongoing monitoring for effective infection control.
- In a study in South Korea, researchers analyzed fecal samples from wild ducks and isolated a low-pathogenic avian influenza H5N3 virus, identifying its genetic characteristics and origins.
- The isolated H5N3 virus exhibited unique features compared to previous strains, indicating that it emerged from new genetic reassortments with viruses from Eurasia in 2018, rather than being derived from older Korean strains.
Article Synopsis
- * Molecular analysis showed that while the HA and NA genes of the H7N3 isolate belonged to the Central Asian lineage, the internal protein genes were linked to the Korean lineage, indicating its LPAIV nature with specific genetic markers.
- * The study found that this strain had high genetic similarities to previous isolates, highlighted its potential for mutations, and emphasized the importance of monitoring avian influenza viruses in wild birds to prevent outbreaks.
Article Synopsis
- - H1N1, a subtype of the influenza A virus, has caused major pandemics in the past and continues to circulate among various animal populations, specifically wild birds, as evidenced by recent research from Korea.
- - Two H1N1 isolates from wild birds in Korea (KNU18-64 and WKU19-4) were studied, revealing distinct mutations affecting their virulence and replication rates, with KNU18-64 showing adaptations for mammal infection.
- - The findings emphasize a link between flu viruses in Korea and the U.S., suggesting a potential for new strains to emerge, highlighting the necessity for ongoing monitoring of influenza in wild bird populations.
Intervirology
January 2020
Article Synopsis
- A significant percentage (3% to 28%) of individuals infected with the chikungunya virus (CHIKV) show no symptoms, highlighting the need for better screening methods beyond traditional diagnostic tests like ELISAs.*
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- This study developed two new monoclonal antibodies targeting CHIKV's E1 protein and utilized them in a fluorescence-linked immunosorbent assay (FLISA), which proved to be more effective than ELISA in detecting the virus.*
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- FLISA demonstrated a lower limit of detection, allowing it to identify CHIKV more accurately in human samples, outperforming ELISA, especially in the presence of human sera and blood.*
J Biomed Nanotechnol
June 2019
Article Synopsis
- Avian influenza (AI) remains a significant health threat despite advancements in diagnostic methods, particularly due to the lack of reliable detection systems for the H5 subtype.
- A new peptide aptamer, P1, was developed through bioinformatics to specifically recognize the H5 strain, demonstrating improved detection capabilities compared to existing methods.
- The study's methods, including immunoassays and molecular docking, confirmed that P1 outperformed traditional antibody-linked tests, suggesting its potential for more effective diagnosis of H5N3 infections.
