[Baldo and Ante Bibica, Father and Son - Two Physicians from Dubrovnik].

Medicine and physicians in Dubrovnik during the last two centuries, i.e. in the period after the dissolution of the Republic of Dubrovnik by Napoleon's Army, have attracted less interest among medical historians.

[Dr Fran Mandić (1851 - 1924): A Reputed Physician from Kastav and "Croatian Consul" in Trieste].

Born in Istria, then part of the Austro-Hungarian Empire, Fran Mandić (1851-1924) finished a Croatian grammar school in Rijeka and studied medicine in Graz, Austria and in Prague, Bohemia. After graduation, he settled in Trieste, a major Austrian port, where he spent his entire career. After a period in the State Hospital in Trieste, Mandić ran his own practice and held a position of medical adviser of the Austrian State Railway in Istria.

[Dr Anto Marić (1897-1982): a journey from alcohology and dermatovenereology to psychiatry and balneology].

Dr Anto Marić (1897-1982) was born in Vukšić in Bosnia. He completed medical studies in Vienna and Prague. He published his results from the Department for dermatovenerology at Sarajevo State Hospital, Bosnia.

[Hinko Lehner--the first Croatian logoped].

In his career, somewhat longer than 22 years, Lehner was frequently transferred from place to place. Beside working as municipal and county physician he worked also as a spa doctor. Very much interested in the stuttering treatment, his own problem that he had solved during his student period in Vienna, he kept trying to sensitize his fellow-doctors, teachers, but also the Croatian authorities for this problem.

[Dr. Bruno Curinaldi (1854-1944): from Zadar over Mostar to Sarajevo].

Dr Curinaldi was a fortunate combination of Italian background, Austro-Hungarian education, and life in a Croatian community where Catholicism met Islam. In a word, he was a genuine European multicultural intellectual. Ninety years of life and sixty-six years of medical career from Zadar to Mostar and to Sarajevo at the turn of the 20th century speak not only about his personal development and dilemmas, but also about social turmoils of the times.

Josip Berlot (1895-1975)- from immunology to ecology.

Born in Rijeka and studied medicine in Vienna, Paris and Prague. He started his medical career in Belgrade State Hospital in 1920 but since 1922 he worked as an assistent at the State Institute of Epidemiology in Zagreb. In 1924 he was sent to USA to specialize in bacteriology, serology and immunology.

[Dr. Hugo Gjankovic (Buzet, 18 September 1893--Dubrovnik, 14 May 1981)].

Prof. dr. Hugo Gjanković is among the most prominent Croatian doctors of this century.

[The role of Dr. Vladimir Cepulić in Croatian orthopedics].

Professor B. Spisić is rightly referred to as founder of the Croatian orthopaedics and rehabilitation. Based on the principles formulated by Prof.

[Ventilatory function of the lungs in patients with ankylosing spondylitis].

The ventilatory function of the lung was studied in 100 patients (85 men and 15 women) suffering from ankylosing spondylitis. The mean age of the patients was 48 years (range: 29-72) and the mean duration of the disease was 18 years (range: 4-37). In 74% of the cases there was evidence of impaired ventilatory function of the lung.

Immunosuppression induced by talc granulomatosis in the rat.

Granulomatosis caused by four subcutaneous talc powder-suspension injections induced strong immunosuppression in rats. The disturbance included reduction of mononuclear white blood cell count in the peripheral blood, atrophy of the thymic cortex, spleen enlargement with predominance of red over the white pulp, increase in the number of lymph node germinal centres and a significant delay of the first-set and second-set allograft rejection. Neither phagocytic function of reticuloendothelial system nor erythrocyte count and humoral immune response were found to be altered.

Chromosomal polymorphism in the house mouse (Mus domesticus) of Greece and Yugoslavia.

A total of 88 wild mice from the Dalmatian coast of Yugoslavia (35 animals), and Peloponnesus (30 animals) and Thebes (23 animals) on mainland Greece were karyotyped. In all but five animals Robertsonian translations were found. Mice from the Dalmatian region were homozygous for translocations Rb(5.

H-41, a new minor histocompatibility locus. I. Histogenetic analysis.

The B10.STA12 mouse congenic line inherited from the wild mouse parent not only the H-2w13 haplotype but also an allele at a minor H locus, which we designate H-41. This allele (H-41a) differentiates the B10.

Qa-like genes defined by CTL analysis of B10.W lines.

Twelve responder-stimulator combinations of mouse B10.W strains identical at K, D, and class II loci were tested for the generation of cytolytic T lymphocytes (CTL). No primary CTL could be obtained in any of the combinations but in nine combinations CTL were generated after priming in vivo.

Frequency of responsiveness to the H-Y antigen among the B10.W lines.

B10.W females were immunized against syngeneic male cells (via the footpad and also i.p.

Cytolytic T cells activated by H-2-controlled E molecules cross-react with A molecules.

Cell-mediated lymphocytotoxicity was generated in four strain combinations differing only by the cell-surface expression of the class II E molecule controlled by the H-2 complex. The four combinations were: B10.D2(R107) anti-B10.

An H-2 haplotype possibly derived by crossing-over between (A alpha A beta) duplex and the E beta locus.

The B10.STA62 strain carries the H-2w27 haplotype derived from a wild mouse captured in the vicinity of Ann Arbor, Michigan. Products of two class II loci composing this haplotype, A alpha and A beta, are serologically, biochemically (by tryptic peptide mapping), and functionally indistinguishable from products controlled by the Ab alpha and Ab beta genes of the B10.