A label-free and highly sensitive DNA biosensor based on the core-shell structured CeO-NR@Ppy nanocomposite for Salmonella detection.

A core-shell cerium oxide nanorod@polypyrrole (CeO-NR@Ppy) nanocomposite-based electrochemical DNA biosensor was studied for Salmonella detection. The core-shell CeO-NR@Ppy nanocomposite was prepared by in situ chemical oxidative polymerization of pyrrole monomer on CeO-NRs, which provided a suitable platform for electrochemical DNA biosensor fabrication. The immobilization of ss-DNA sequences onto nanocomposite-coated microelectrode was performed via covalent attachment method.