Publications by authors named "Vu Tuan Anh Nguyen"
Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization.
Van Thien Chi Nguyen Trong Hieu Nguyen Nhu Nhat Tan Doan Thi Mong Quynh Pham Giang Thi Huong Nguyen Thanh Dat Nguyen Van Chu Nguyen Huu Thinh Nguyen Trieu Vu Nguyen Thi Hue Hanh Nguyen Thuy Nguyen Doan Viet Hai Nguyen Vu Tuan Anh Nguyen Bao Toan Nguyen Thanh Nhan Vo Nguyen Thanh Dang Nguyen Minh Nguyen Nguyen Anh Nhu Nguyen Hong-Dang Luu Nguyen Duy Sinh Nguyen Hoai-Nghia Nguyen
Elife
October 2023
Article Synopsis
- The study introduces a new assay called SPOT-MAS that combines multiple analysis techniques to detect different types of cancer using circulating tumor DNA (ctDNA).
- SPOT-MAS was tested on a large group of 738 patients with various cancers and 1550 healthy controls, successfully identifying cancers with a sensitivity of 72.4% and high specificity.
- The assay performs well for early-stage cancers and shows promise for being more cost-effective compared to other ctDNA tests due to its lower sequencing depth requirements.
Long-term Results of Totally Laparoscopic Near-total Gastrectomy for Middle-third Gastric Cancer.
Nguyen Vu Tuan Anh Vo Duy Long Nguyen Lam Vuong Nguyen Viet Hai Ho Le Minh Quoc Doan Thuy Nguyen Nguyen Hoang Bac Nguyen Trung Tin
Surg Laparosc Endosc Percutan Tech
October 2023
Purpose: In recent years, laparoscopic near-total gastrectomy (LnTG) has emerged as a surgical option for gastric cancer in the middle-third of the stomach. However, its application in locally advanced stages presents technical challenges. This study aims to provide a detailed analysis of the operative outcomes and long-term functional and oncological results of totally LnTG in combination with D2 lymphadenectomy for middle-third gastric cancer.
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- Lymph node metastasis can occur in early gastric cancer, even in nodes not near the primary tumor, necessitating careful selection between total gastrectomy (TG) and subtotal gastrectomy (sTG) based on cancer spread.
- A study of 98 patients revealed that 65.3% had metastatic lymph nodes, with higher rates of metastasis increasing with tumor invasion depth, especially in adjacent lymph node stations.
- Results showed that while TG had higher total lymph nodes and positive lymph node rates, the ratio of metastatic lymph nodes was similar between TG and sTG, suggesting that sTG with proper lymphadenectomy is a viable treatment option for certain early-stage gastric cancers.