[Lymphoedema Following Regional Lymph Node Surgery for Breast Cancer].

Background: The treatment of breast cancer is based on the multimodal principle and surgery of regional lymph nodes is an inseparable part of this. Indication criteria are changing constantly folowing advances in other modalities. It is necessary to consider not only the diagnostic or therapeutic benefit but also to take into account adverse effects.

[Failed preoperative lymphoscintigraphy for sentinel lymph node biopsy in breast cancer, possible causes and implications for the surgery - the analysis of 3014 procedures].

Introduction: The aim of the study was to review the cases of sentinel lymph node biopsy for breast cancer in which preoperative lymphoscintigraphy had shown no axillary hot spot; to assess the frequency of failed examinations and possible causes of the failure; to analyze subsequent surgical procedures and hence to provide a general recommendation on what to do in such a situation.

Methods: A retrospective overview of 3014 lymphoscintigraphy examinations at the Masaryk Memorial Cancer Institute from 2001 to 2011 with a more detailed analysis of the cases with axillary hot spot visualization failure.

Results: The axillary hot spot was not shown in 71 examinations (2.

A simple model to assess the probability of invasion in ductal carcinoma in situ of the breast diagnosed by needle biopsy.

Objectives: The aim of the study was to develop a clinical prediction model for assessing the probability of having invasive cancer in the definitive surgical resection specimen in patients with biopsy diagnosis of ductal carcinoma in situ (DCIS) of the breast, to facilitate decision making regarding axillary surgery.

Methods: In 349 women with DCIS, predictors of invasion in the definitive resection specimen were identified. A model to predict the probability of invasion was developed and subsequently simplified to divide patients into two risk categories.

[The number of removed axillary sentinel lymph nodes and its impact on the diagnostic accuracy of sentinel lymph node biopsy in breast cancer].

Introduction: The number of lymph nodes removed during the sentinel lymph node biopsy in patients with breast cancer usually ranges from 1 to 3. In some cases, multiple nodes are identified and removed, which could be associated with increased risk of postoperative morbidity. The objective of the study was to assess the number of sentinel lymph nodes removed in patients treated in our hospital, to analyze factors that may influence the amount of the removed nodes, and to find if there is an upper threshold number of lymph nodes that should be removed without sacrificing the diagnostic accuracy of the sentinel lymph node biopsy.

[What patients need to know before their breast cancer surgery].

Backgrounds: The quality of health care depends not only on physicians' medical skills but also on proper patient education. The aim of the study was to ascertain the types of information required by women before they start their breast cancer treatment.

Patients And Methods: Before a surgery, 254 patients with early breast cancer treated primarily by surgery obtained an originally developed questionnaire containing information topics assumed to be important.

[Accuracy of preoperative establishment of invasive breast carcinoma size using ultrasound and mammography].

Introduction: Accurate preoperative assessment of breast cancer size is important for choosing appropriate surgical treatment. Mammography and ultrasonography are the most widely used breast imaging techniques. The aim of this study was to compare the tumour size measured by these two modalities with the pathological size of native specimen.

[Visibility in ultrasonography as the strongest invasion predictor in ductal carcinoma in situ in a retrospective study].

Background: Detection of ductal carcinoma in situ (DCIS) of the breast has markedly increased since the introduction of screening mammography. Current management of this preinvasive lesion comprises complete margin-free resection of the tumour. Lymph node staging is still not indicated as a standard procedure but we can find published cases of pure DCIS with lymph node involvement as well as a high proportion of invasive carcinomas in the final histopathology.

Predicting non-sentinel lymph node status after positive sentinel biopsy in breast cancer: what model performs the best in a Czech population?

Several models have previously been proposed to predict the probability of non-sentinel lymph node (NSLN) metastases after a positive sentinel lymph node (SLN) biopsy in breast cancer. The aim of this study was to assess the accuracy of two previously published nomograms (MSKCC, Stanford) and to develop an alternative model with the best predictive accuracy in a Czech population. In the basic population of 330 SLN-positive patients from the Czech Republic, the accuracy of the MSKCC and the Stanford nomograms was tested by the area under the receiver operating characteristics curve (AUC).

[Surgical treatment of breast cancer in the Masaryk Memorial Cancer Institute].

Breast cancer represents the most frequent malignancy in women in the Czech Republic. Although surgery plays the basic role in the therapy of its early stages there hasn't existed any specialized training in surgical oncology in our country so far. Majority of patients are surgically treated at departments of general surgery where sometimes outdated procedures are used as we know from our own experience.