Publications by authors named "Vrati M Mehra"

Early pregnancy is a critical period often accompanied by complications like early pregnancy loss. Early Pregnancy Assessment Clinics (EPACs) provide specialized and compassionate care to those experiencing these complications. First introduced in the United Kingdom, EPACs have been found to improve quality of care, reduce wait times, and cut costs.

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  • Recent studies show that there is a lack of awareness among Canadian women about the benefits of folic acid (FA) supplementation before pregnancy, particularly using data from the 2017-2018 Canadian Community Health Survey.
  • Approximately 22.1% of women reported being unaware of the benefits of FA.
  • Factors such as lower education levels, lack of access to healthcare, low household income, and immigrant status were linked to higher rates of unawareness, highlighting the need for targeted public health campaigns addressing social disadvantages.
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  • The study focused on how men with oligospermia (low sperm count) might develop idiopathic secondary azoospermia (ISA) over time, looking for risk factors in a group of 1,056 patients.
  • Results showed that men with extremely severe oligospermia (≤1 M/ml) had a significantly higher chance (21.1% after 3-5 years) of developing ISA compared to those with severe (4.8%) and mild oligospermia (0%).
  • The findings emphasize the need for sperm banking in men with extremely low sperm counts and low testosterone levels, as they are at a higher risk of becoming azoospermic, while those with >1 M/ml are less
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Background: Paternal age association with sperm parameters has been previously studied, demonstrating a decrease in semen volume, sperm motility, and sperm morphology, but not in sperm concentration. However, scarce data exists on the individual intra-personal changes in semen parameters with time.

Study Design: Retrospective cohort study.

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Objectives: The objective of this study was to gather Ontario clinicians' and public members' views on the design of a pre-conception patient education program.

Methods: In this mixed-methods study, online surveys comprised of rank order, multiple choice, and short answer questions were completed by clinicians and public members. Semi-structured focus groups consisting of 2-6 participants each were then held via videoconference.

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Objectives: With growing incidence of type 1 diabetes (T1D), type 2 diabetes (T2D), and gestational diabetes, more women are expected to spend a larger proportion of their reproductive years living with a diabetes diagnosis. It is important to understand the long-term implications of premenopausal diabetes type on women's reproductive health including their age at natural menopause (ANM).

Methods: Baseline data from the Comprehensive Cohort of Canadian Longitudinal Study on Aging were used.

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Background: The recreational use of cannabis was legalized across Canada in October 2018. While many people use cannabis without harm, adverse outcomes have been noted in a few populations, including middle-aged and older adults. Given that the current literature has neglected to study cannabis use among this population and between sexes, the objective of our study was to identify the prevalence, characteristics, and patterns of cannabis use among middle and older aged males and females prior to legalization in Canada.

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Cardiac rehabilitation is a comprehensive model of secondary prevention proven to reduce mortality and morbidity. The World Health Organization is developing a Package of Rehabilitation Interventions for implementation by ministries of health as part of universal healthcare across the continuum. Through a systematic review, we sought to identify the best-quality cardiac rehabilitation guidelines, and extract their recommendations for implementation by member states.

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Background: E-cigarettes have grown in popularity around the world since 2003. Although marketed as a smoking cessation tool, e-cigarettes can lead to tobacco cigarette smoking in youth. In Canada, among all age groups, youth and young adults have the highest prevalence of e-cigarette use.

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Background: Ontario is home to the largest number of immigrants in Canada. However, very little is known about their dental care utilization patterns. The purpose of this study is to determine the prevalence of poor dental health care use among the immigrant population of Ontario and how various socio-demographic, socio-economic and health-related factors are associated with it.

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Ontario has the largest Indigenous population in Canada. This study aims to examine the prevalence and factors associated with poor dental care use amongst the Indigenous in Ontario. Data from the 2014 cycle of the Canadian Community Health Survey was used.

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