[Neuro-anatomy of retinoblastoma].

In four cases of retinoblastoma examined with the method of Golgi we have only found vessels and glial elements at different stages of differentiation. Moreover, in the areas containing typical rosettes, Golgi method revealed some isolately impregnated elements resembling photoreceptors in evolution. Within the retina abuting on the tumor were found only normal retinal nervous elements.

The effect of liquid silicone on the corneal endothelium in rabbits. A comparative specular microscopic and histopathologic study.

Specular microscopic and histopathologic findings in the corneal endothelium were compared after the injection of liquid silicone into the anterior chamber of both eyes in 15 rabbits. The findings demonstrated serious damage to the endothelium in the area of contact of liquid silicone with the posterior surface of the cornea and disclosed some problems in the interpretation of specular microscopic findings. An abnormal endothelial mosaic can be probably found even in a zone of preserved intercellular borders or in a zone with a relief of the bases of extinct endothelial cells.

"Displaced nerve cells" in the human retina.

Several kinds of nerve cells in the vertebrate retina can be found in retinal layers other that to which they belong. The present paper discusses all such cells within the human retina, as the author was able to stain them selectively using different neurohistological methods.

[Ophthalmopathology of Wegener granulomatosis].

The authors present a detailed report on the histological findings in the anterior and posterior segments in Wegener's granulomatosis. Histopathologically the granuloma is nonspecific, usually consisting of histiocytes and lymphocytes. There were no giant cells in the cellular infiltrations.

Early differentiation of the human retina. A neurohistological study.

A series of retinas from 30 human embryos, ranging in total length from 10 to 40 mm (i.e., to the end of gestation month 2), were successfully stained by the Golgi method and then examined and compared with routinely stained specimens from pertinent stages.

[Human optic nerve head lesions in the aged (author's transl)].

Following preliminary studies on human optic nerve head lesions in the aged, 109 optic nerve heads were examined to determine the frequency, localisation, and time of appearance of the two types of senile degenerative lesions described in these initial studies. Frequency curves are presented, and results discussed and compared with data reported in the published literature.

Diabetic changes of the extra-ocular muscles in man.

Axonal and myelin changes of the degenerative type were found in the extra-ocular muscles of 21 out of 23 diabetics of all ages (30--74 years). In all these 21 cases both axonal and myelin changes were observed; they did not correlate with the duration, degree of severity or treatment of diabetes. In 19 of the 23 cases (82.

Anterior chamber angle recession in uveal melanomas.

Sixteen uveal melanomas in celloidin sections and eight other fresh cases of melanoma were examined using different clinical and histological methods. A recession of the lateral border of the anterior chamber angle was found in most of them. The grade of this distortion varied from very deep to insignificant, but was apparent in most cases.

Age changes of the human optic nerve head. A neurohistologic study.

Eleven human optic nerves from subjects in different decades ranging from the fifth to the ninth were investigated with the silver carbonate method to establish the pattern and frequency of age changes within the optic nerve head and their relationship with the glaucomatous excavation. It has been found that despite the occurrence of age degeneration at the same level of the cribriform lamina, there are definite anatomical differences as compared with glaucoma changes, especially regarding the distribution of axonal damage.

Ring-shaped acid burns of the rabbit cornea.

In the extension of our previous work on alkali burns of the rabbit cornea we have studied acid burns of the rabbit cornea using a ring-shaped chromoatographic paper soaked with solutions of different kinds of acids. The ensuing changes were studied with the silver methods of McGovern and Jabonero.

Ring-shaped alkali burns of the rabbit cornea. III. Late phase of the stroma reaction.

The present paper deals with late changes of the corneal stroma after alkali burns from the 5th day after the injury up to the 58th day. As has been pointed out in a previous paper, between the 3rd and 5th day the process of healing within the corneal stroma changes and at the end a dense scar ensues.

Glaucomatous cupping of the human optic disk: a neuro-histologic study.

The optic nerve and optic disk in 20 cases of glaucoma were examined neurohistologically. The interruption of retinal axons was found localized in a narrow transversal strip at the level of the posterior part of the lamina cribrosa and immediately behind it. Retinal axons anterior to this zone were mostly intact as long as their ganglion cells of origin were preserved.

Ring-shaped alkali burns of the rabbit cornea. II. Early changes of the corneal stroma.

Corneas of 32 rabbits were coagulated in a circular zone of 1 mm width and 10 mm diameter. The results of the experiment showed sharply limited injury throughout the entire depth of the cornea without lateral diffusion. The reactions of the corneal stroma during the first three days are described and discussed.