[Assessment of ultrastructural changes in the contractile apparatus of cardiomyocytes after heart contusion].

Experimental simulation of heart contusion accompanied by acute insufficiency of myocardial contractility was followed by examination of myocardial tissue samples using transmission electron microscopy. Analysis of microstructural changes in cardiomyocytes revealed characteristic defects in their contractile apparatus. The results were used to substantiate mechanisms underlying acute insufficiency of myocardial contractility resulting from heart contusion.

[Histochemical study of the myocardium structure in the heart contusion].

The experimental modeling of heart contusion which was accompanied by ventricular fibrillation development was performed in Wistar rats, with the electrocardiographic study and subsequent histological and histochemical examination of the myocardium samples. Following heart contusion, acute circulatory disturbances, muscle fiber fragmentation, cardiomyocyte overcontraction or relaxation were detected in the myocardium. Also, the increase of total and intracellular calcium ion content in the myocardium was demonstrated.

[The use of a morphohistochemical method for the diagnosis of heart contusion].

This morphohistochemical study was carried out using myocardial tissue samples obtained from subjects with heart contusion. The aim of the study was to elucidate the cause of ventricular fibrillation associated with alternative myocardial insufficiency. It is concluded that changes of Ca2+ ion content in the myocardial tissue may be one of the factors contributing to the development of ventricular fibrillation.