[Ambient air interference in oxygen intake measurements in liquid incubating media with the use of open polarographic cells].

A model of oxygen intake by aerobic bio-objects in liquid incubating media was applied to investigate the influence air-media interface area on accuracy of measuring the oxygen intake and error value. It was shown that intrusion of air oxygen increases the relative error to 24% in open polarographic cells and to 13% in cells with a reduced interface area. Results of modeling passive media oxygenation laid a basis for proposing a method to reduce relative error by 66% for open cells and by 15% for cells with a reduced interface area.

[Polyamine levels in cadaveric bone marrow].

The content of polyamines in cadaveric bone marrow was measured before and after cryopreservation. The content of some polyamines was found to depend on the morphologic and functional preservation of bone marrow elements. It is concluded that the content of some polyamines may serve as criterion of cell destruction and proliferative potencies of bone marrow.

[The character of quantitative changes in some parameters of polyamine metabolism of the blood in patients with chronic leukemia].

Content of polyamines and some patterns of metabolism related to their synthesis and catabolism were studied in blood of patients with chronic myeloleukemia and chronic lympholeukemia. Free polyamines as well as activity of diamine oxidase were distinctly increased in blood, while concentration of total diamino acids was simultaneously decreased in blood serum of the patients as compared with that of healthy persons. Specific type of the quantitative alterations was responsible for efficiency of chemotherapy in these patients.

[Significance of polyamines for the early diagnosis of spontaneous hemoblastoses in AKR mice].

Polyamines levels were studied in various tissue specimens obtained from high-leukemia AKR mice aged 12 months and less. Organ tissues of leukemic animals revealed increased levels of polyamines and changes in their profile. In symptomatic mice, this was matched by relevant morphologic changes.

[Polyamines as a prognostic criterion of the duration of clinico-hematologic remission in acute leukemia in children].

The authors reported the results of retrospective analysis of the level of polyamines in urine and the duration of clinicohematological remission in 25 AL children aged 3 to 14. Of this number 23 patients suffered from acute lymphoblastic leukemia, 2--from acute myeloblastic leukemia. Direct correlation between polyamine changes during a course of chemotherapy and the duration of remission was established.

[Urinary excretion of polyamines in burn patients].

Excretion of spermine, spermidine and putrescine with urine was studied in 38 patients (21-79 years old) with thermic burns of various degree. Certain differences were detected in excretion of the polyamines with urine depending on severity, step and outcome of the disease. In the course of the disease both low and extremely high level of the polyamines, found in urine during thermic shock, were unfavourable prognostically.

[Polyamine levels of the blood of healthy persons].

A fraction content of free and conjugated polyamines was studied in whole blood of 70 practically healthy persons. Spermine and spermidine were mainly found among the polyamines with some quantitative predominance of the latter. Putrescine was not observed in blood or its amount was not detected by means of spectrophotometry.

[T- and B-lymphocyte counts and their function in patients with primary liver cancer and alveococcosis].

The levels of T- and B-lymphocytes were assayed and their functional activity studied in 23 patients with primary cancer and 21 cases of alveococcosis of liver. The lowered levels of T-lymphocytes in both groups and the decreased C3-fraction of B-lymphocytes in primary cancer of the liver were observed. Considerable changes in serum immunoglobulin system, i.