Publications by authors named "Vorilhon C"

Article Synopsis
  • Cardiac fibrosis is linked to heart failure and poor outcomes; previous research on fibrosis biomarkers predicting response to cardiac resynchronization therapy (CRT) has been inconclusive.
  • A study involving 60 patients evaluated various fibrosis biomarkers before CRT, finding that 63% had a positive response after six months, indicated by specific heart health criteria.
  • Responders had significantly lower levels of fibrosis biomarkers, particularly PICP and PIIINP, suggesting that assessing these biomarkers pre-CRT may enhance patient selection for better treatment outcomes.
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Background: The prevalence and incidence of heart failure (HF) in elderly patients are increasing worldwide. Management of HF with reduced ejection fraction (HF-REF) in patients aged 80 years or more follows international guidelines, despite the lack of a dedicated study in this frail population.

Aims: To determine whether optimized management of HF-REF in patients aged 80 years or more can improve quality of life at 6 months.

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Background: The Education Thérapeutique des patients Insuffisants Cardiaques (ETIC; Therapeutic Education for Patients with Cardiac Failure) trial aimed to determine whether a pragmatic education intervention in general practice could improve the quality of life of patients with chronic heart failure (CHF) compared with routine care.

Results: This cluster randomised controlled clinical trial included 241 patients with CHF attending 54 general practitioners (GPs) in France and involved 19 months of follow-up. The GPs in the Intervention Group were trained during a 2-day interactive workshop to provide a patient education programme.

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New-onset left bundle branch block (LBBB) is a specific concern of transcutaneous aortic valve implantation (TAVI) given its estimated incidence ranging from 5% to 65%. This high rate of occurrence is dependent on the type of device used (size and shape), implantation methods, and patient co-morbidities. The appearance of an LBBB after TAVI reflects a very proximal lesion of the left bundle branch as it exits the bundle of His.

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Article Synopsis
  • - Pheochromocytoma and paraganglioma (PPG) are rare tumors that release catecholamines and can cause severe cardiomyopathies, often diagnosed late, with patients experiencing acute symptoms like high blood pressure and chest pain.
  • - A systematic review collected 145 case reports of cardiomyopathy linked to PPG, noting similar initial symptoms between Takotsubo Cardiomyopathies (TTC) and other catecholamine-related cardiomyopathies (CC), but a higher occurrence of acute pulmonary edema in CC.
  • - TTC patients showed better recovery rates for left ventricular function both before and after surgical removal of the tumors, highlighting the importance of diagnosing PPG in cases of unexplained dilated cardi
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Purpose: Heart failure (HF) is a major public health issue. This study conducted a real-life analysis of the impact of clinical characteristics and medical management of HF on its prognosis.

Methods: Analysis was based on the EGB ("Echantillon Généraliste des Bénéficiaires") database.

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Purpose: The aim of the study was to assess the impact of clinical characteristics and management on the mid- to long-term follow-up prognosis of unselected over-80-year-old patients hospitalized for a first heart failure (HF) episode in a real-life setting. Despite the increasing proportion of HF patients over 80 years of age, the latter remain a poorly studied population.

Methods: Analysis was based on the EGB ("Echantillon Généraliste des Bénéficiaires") database.

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Pericardial mesothelioma is a rare form of pericardial tumor. The invasive investigations such as biopsy make the diagnosis. Non-invasive imaging techniques provide valuable information about its diagnosis and its clinical impact.

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Background: An aging population and better management of various heart diseases explain the exponential growth in incidence and prevalence of chronic heart failure, with poor prognosis and heavy health costs. Medical management is codified in international guidelines. The management of heart failure in over-80 year-old patients follows these guidelines, but no clinical trials have been able to confirm benefit.

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