Addressing the need for accessible SARS-CoV-2 testing, carboxy-PEG 12-thiol functionalized gold nanoparticles conjugates were developed for rapid point-of-care (POC) detection against SARS-CoV-2 spike protein, pseudo-SARS-CoV-2, and authentic Beta SARS-CoV-2 virus particles. These conjugates leverage gold nanoparticles (AuNPs) as signal transducers, cross-linked to either angiotensin-converting enzyme 2 (ACE2) or SARS-CoV-2 spike protein receptor-binding domain (RBD) antibodies as bioreceptors and showed a distinct color shift from pink to blue. To assess their POC feasibility, the conjugates were integrated into facemasks and breathalyzers, wherein aerosolized SARS-CoV-2 antigens were successfully detected, producing a color change within 10 and 30 minutes for the breathalyzer and facemask prototypes, respectively.
View Article and Find Full Text PDFThe search for a viable photocatalyst for water remediation is ongoing and in recent times the efforts have predominantly focused on improving the limitations of the TiO photocatalyst. This paper reports a dual strategy for improving the photocatalytic properties of TiO. The first strategy is to dope up to 30% of W and Zn into the crystal lattice of TiO using the resin gel technique to synthesize quaternary mixed metal oxides (QMMOs).
View Article and Find Full Text PDFOne pot synthesis of a polypyrrole, polyaniline and Fe nano-composite (Fe-PPY/PANI) was achieved by polymerizing aniline and pyrrole with FeCl followed by the reduction of Fe to Fe with NaBH. PPY/PANI was synthesized the same way as Fe-PPY/PANI, except that all the FeCl was removed by rinsing. The presence of Fe was demonstrated using several analytical techniques; this was shown in comparison to materials that are without Fe.
View Article and Find Full Text PDFThis work reports the electrocatalysis of bisphenol A on Ni(II) tetraamino metallophthalocyanine (NiTAPc) polymer modified gold electrode containing Ni-O-Ni bridges (represented as Ni(OH)TAPc). The Ni(II)TAPc films were electro-transformed in 0.1 mol L(-1) NaOH aqueous solution to form 'O-Ni-O oxo bridges', forming poly-n-Ni(OH)TAPc (where n is the number of polymerising scans).
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