Cytokine profile in multiple sclerosis patients with and without Covid-19.

Objective: Aim: To investigate the possible effect of COVID-19 disease on cytokine profile and some circulating growth factors in patients with multiple sclerosis (MS).

Patients And Methods: Materials and Methods: Serum cytokine levels as well as growth factors content were assessed be means of a solid phase enzyme linked‑immunosorbent assay in 97 MS patients of which 41 had and 56 did not have confirmed COVID-19 in the past 4-6-month period, and 30 healthy individuals who were age‑, and gender‑matched.

Results: Results: Some proinflammatory cytokine (such as TNFα, IFNγ) levels were higher while anti-inflammatory cytokine, namely IL‑4, was lower in MS patients compared to controls indicating Th1/Th2 imbalance.

SIMULATION TRAINING AND VIRTUAL PATIENTS AS A COMPONENT OF CLASSROOM TRAINING OF FUTURE DOCTORS UNDER COVID-19 CONDITIONS.

Objective: The aim: To present and substantiate the theoretical and applied aspects of the organization of simulation training for higher education applicants in the field of health care based on the analysis and generalization of the experience of the Bogomolets National Medical University.

Patients And Methods: Materials and methods: To perform the set tasks, the following theoretical and empirical methods of scientific research were used: system analysis; comparison and generalization; bibliosemantic method; the analysis and simulation methods.

Results: Results: The experience of organizing simulation training for higher education students in the field of health care was analyzed and summarized.

Prevention of main dental diseases in children using herbal tea «dentesvita».

Introduction: Transcarpathian region refers to the climate-geographic zone with a low level of fluoride and iodine in the environment and as shown by the epidemiological survey «very high» according to WHO criteria for the level of intensity of main dental diseases. With the purpose of directing the implementation of the state policy in the field of health care and for the prevention of dental diseases, the industrial release of a functional food product - «DentesVita» enriched with iodine and fluorine - has been adjusted. The aim: Was to study the effectiveness of the use of functional food product - DentesVita for the prevention of dental caries in children.

Relationship between idiopathic scoliosis of the spine and dentognathic anomalies in adolescents.

Objective: Introduction: According to the data of the national statistics, the disease of the musculoskeletal system among the teenagers takes the third place among the main types of diseases. So, we decided to analyze and study the connection between the idiopathic scoliosis of the spine and dentognathic anomalies in children aged 12-15 years old in Uzhhorod (Ukraine). The aim: To determine the characteristic violations of the dentognathic system in adolescents with idiopathic scoliosis of the spine, taking into account the anatomical type of lesion.

Prevalence of main dental diseases in children who live in conditions of biogeochemical fluorine and iodine deficiency.

Background: Dental status is one of the main indicators of overall health. We examined it in children aged 6-15 years who live in conditions of biogeochemical fluorine and iodine deficiency (Transcarpathian region, Ukraine), to improve the quality of dental care.

Materials And Methods: In this cross sectional study To assess the state of teeth, we used indicators recommended by the WHO Expert Committee.

Socio-psychological aspects in the prevention of dental diseases.

Objective: Introduction: Measures to prevent dental diseases are included in the list of medical care provided by dentists. Modern socio-economic transformations, including in health care, have contributed to the gradual evolution of the patient from the recipient of medical care to the consumer of services. The aim: To study the position of patients regarding the need and effectiveness of preventive dental care.