NESFATIN-1 ACTIVITY IN THE BLOOD SERUM IN PATIENTS WITH CHRONIC HEART FAILURE OF ISCHEMIC ORIGIN AGAINST THE BACKGROUND OF TYPE 2 DIABETES MELLITUS AND OBESITY.

Objective: The aim: To study the nesfatin-1 activity in the blood serum of patients with chronic heart failure (CHF) of ischemic origin against the background of such metabolic disorders as type 2 diabetes mellitus (T2DM) and obesity.

Patients And Methods: Materials and methods: 154 patients with CHF were examined, and divided into 4 groups, according to the presence of metabolic disorders. Group 1 included patients with CHF on the background of coronary heart disease (CHD) and T2DM and obesity (n=42).

ESTIMATION OF PREDICTORS AND DEVELOPMENT OF PROGNOSTIC MODEL FOR COMORBID COURSE OF DIABETES MELLITUS AND ISCHEMIC HEART DISEASE.

Objective: The aim: To determine predictors and develop the model of prognosis of comorbidity of ischemic heart disease and type 2 diabetes mellitus.

Patients And Methods: Materials and methods: 126 patients were involved in the study and divided into three groups. Main group involved 70 patients with comorbid T2DM and IHD; comparison group included 36 IHD-only patients; 20 patients were included into control group.