STUDY OF IMMUNE-INFLAMMATORY RESPONSE CHANGES IN ORAL FLUID IN PATIENTS WITH DISEASES OF PERIODONTAL TISSUES IN COMBINATION WITH GENERAL SOMATIC PATHOLOGY.

Objective: The aim: To determine the concentration of markers of the immune-inflammatory response (IL-1β, IL-10, IL-1β / IL-10, hsCRP) in oral fluid in patients with diseases of periodontal tissues in combination with general somatic pathology.

Patients And Methods: Materials and methods: The study was conducted at Danylo Halytsky Lviv National Medical University, Department of therapeutic dentistry FPGE, Lviv, Ukraine. The patients were divided into two groups: the main group - 144 patients (with periodontal tissue diseases on the background of general somatic pathology) and the control group - 30 somatically and dentally healthy persons, in whose oral fluid was determined the concentration of IL-1β, IL-10, hsCRP by the enzyme immunoassay method.

Prevalence of the generalized periodontitis in patients with different groups blood in depending on age and periodontal biotype.

Objective: The aim of the study was to investigate the prevalence of generalized periodontitis depending on age and biotype of periodontium.

Patients And Methods: Materials and methods: We examined 855 males aged 20-55 years, who were divided into 2 groups: the main group - 570 surveyed with a generalized periodontitis, the comparison group - 285 dental healthy individuals.The diagnosis of generalized periodontitis was established by the classification Danilevsky M.