In-rubber properties of vulcanizates deteriorate in the presence of incorporated recycled ground rubber (GR). This behavior is partly explained by a possible diffusion of sulfur from the rubber matrix into the GR. Therefore, the sulfur concentration and, thus, the crosslink density in the matrix are reduced.
View Article and Find Full Text PDFMost anti-cancer modalities are designed to directly kill cancer cells deploying mechanisms of action (MOAs) centered on the presence of a precise target on cancer cells. The efficacy of these approaches is limited because the rapidly evolving genetics of neoplasia swiftly circumvents the MOA generating therapy-resistant cancer cell clones. Other modalities engage endogenous anti-cancer mechanisms by activating the multi-cellular network (MCN) surrounding neoplastic cells in the tumor microenvironment (TME).
View Article and Find Full Text PDFThe purpose of this study was to explore the relationship between the forces applied to the starting blocks and the start performances (SPs) of amputee sprinters (ASs) and non-amputee sprinters (NASs). SPs of 154 male and female NASs (100-m personal records [PRs], 9.58-14.
View Article and Find Full Text PDFCancer Epidemiol Biomarkers Prev
November 2015
Background: Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical.
Methods: We performed a genome-wide survival analysis of cause-specific death in 24,023 prostate cancer patients (3,513 disease-specific deaths) from the PRACTICAL and BPC3 consortia.