The CO-MIND Study: Chronic Obstructive Pulmonary Disease Management in Daily Practice and Its Implications for Improved Outcomes According to GOLD 2019 Perspective.

Purpose: GOLD 2019 proposed a novel treatment decision tool for follow-up based on the predominant trait (exacerbation or dyspnea) of patients, alongside treatment escalation and de-escalation strategies. This study was designed to provide an up-to-date snapshot of patient and disease characteristics, treatment pathways, and healthcare resource use (HRU) in COPD in real life, and comprehensively examine patients considering GOLD 2019 recommendations.

Patients And Methods: This mixed design, observational, multicenter (14 pulmonology clinics) study included all patients with a documented COPD diagnosis (excluding asthma-COPD overlap [ACO]) for ≥12 months, aged ≥40 years at diagnosis who had a COPD-related hospital visit, spirometry test and blood eosinophil count (BEC) measurement under stable conditions within the 12 months before enrollment between February and December 2020.

Consensus on mild asthma management: results of a modified Delphi study.

Objective: In order to understand the role of regular controller inhaled corticosteroids (ICS) versus as-needed ICS-formoterol in managing mild asthma, we performed a modified Delphi procedure.

Methods: Opinions from 16 respiratory experts to three surveys and during a virtual scientific workshop helped to develop final consensus statements (pre-defined as 70% agreement).

Results: Thirteen participants completed all rounds (response rate 81%).

Cost-Effectiveness Comparison of Pneumococcal Conjugate Vaccines in Turkish Children.

Background: The 13-valent pneumococcal conjugate vaccine (PCV13) is used for universal infant vaccination in Turkey.

Objectives: To assess the cost effectiveness of replacing PCV13 with pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV).

Methods: A Markov cohort model with monthly cycles following 1 cohort of infants over a 10-year time horizon was used.

A case of bilateral uveitis and optic disc swelling with Chiari I malformation.

We report a case of bilateral uveitis and optic disc swelling with Chiari I malformation. A 16-year-old girl was admitted to our clinic due to conjunctival hyperaemia and blurred vision in her right eye. Ophthalmologic and systemic examinations were performed.

Multidetector CT technique and imaging findings of urinary stone disease: an expanded review.

Unenhanced computed tomography (CT) is currently being widely used for the evaluation of patients presenting with acute flank pain. A variety of primary and secondary findings detected on unenhanced CT contribute not only to the diagnosis but also to the treatment plan. This review includes primary and secondary multidetector CT imaging findings of urinary stone disease, potential pitfalls with exquisite images of sample cases, and a brief review of radiation dose reduction and contrast administration strategies.