Publications by authors named "Volga M Saini"
Article Synopsis
- Epithelial ovarian carcinoma (EOC) is a significant health threat for women, being the most deadly gynecological cancer primarily due to late diagnoses and high recurrence rates.
- Circulating tumor cells (CTCs) are a rare type of cancer cell that spread into the bloodstream and may serve as useful biomarkers for monitoring EOC, as they can be obtained through minimally invasive liquid biopsies.
- Despite their potential, the unique characteristics of EOC complicate the detection and analysis of CTCs, posing challenges for their use in clinical settings.
Circulating tumor cells (CTCs) have potential as diagnostic, prognostic, and predictive biomarkers in solid tumors. Despite Food and Drug Administration (FDA) approval of CTC devices in various cancers, the rarity and heterogeneity of CTCs in lung cancer make them technically challenging to isolate and analyze, hindering their clinical integration. Establishing a consensus through comparative analysis of different CTC systems is warranted.
View Article and Find Full Text PDFIntroduction: MicroRNAs (miRNAs) have been shown to be altered in both CVD and T2DM and can have an application as diagnostic and prognostic biomarkers. miRNAs are released into circulation when the cardiomyocyte is subjected to injury and damage.
Objectives: Measuring circulating miRNA levels in human plasma may be of great potential use for measuring the extent of damage to cardiomyocytes and response to exercise.