Publications by authors named "Vogel F"

High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.

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  • The study uses mobile in situ atmospheric concentration measurements to estimate methane emissions from urban waste treatment facilities in Southern Ontario, Canada, focusing on high-resolution improvements to existing methane inventories in the Greater Toronto Area (GTA).
  • Over seven years, researchers collected extensive mobile survey data from multiple types of waste facilities, representing 77% of active landfills in Southern Ontario, revealing that emissions from closed landfills are significantly lower than previously estimated.
  • The updated methane emissions data led to a 54% reduction in solid waste emissions estimates and a 35% overall decrease in anthropogenic methane emissions in the GTA, highlighting discrepancies between inventories and actual measured emissions.
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Toxoplasmosis is a parasitic disease caused by infection with Toxoplasma gondii, capable of infecting a wide range of hosts. The parasite exhibits a broad genetic diversity, necessitating genotypic characterization for genotype identification and associations with epidemiological information. Therefore, the Restriction Fragment Length Polymorphism (RFLP) technique is used for characterization.

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  • * A study examined 200 dogs in Rio Grande do Sul, Brazil, for the presence of Leishmania spp., using PCR techniques; 26.5% tested positive, all for L. infantum, with an average age of 5.08 years among the infected.
  • * Clinical signs in infected dogs varied, with some showing symptoms like hepatomegaly and anemia; notable pathological findings included evidence of distemper and meningitis in certain cases.
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Neuroscience education is challenged by rapidly evolving technology and the development of interdisciplinary approaches for brain research. The Human Brain Project (HBP) Education Programme aimed to address the need for interdisciplinary expertise in brain research by equipping a new generation of researchers with skills across neuroscience, medicine, and information technology. Over its ten year duration, the programme engaged over 1,300 experts and attracted more than 5,500 participants from various scientific disciplines in its blended learning curriculum, specialised schools and workshops, and events fostering dialogue among early-career researchers.

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A search for the exclusive hadronic decays W^{±}→π^{±}γ, W^{±}→K^{±}γ, and W^{±}→ρ^{±}γ is performed using up to 140  fb^{-1} of proton-proton collisions recorded with the ATLAS detector at a center-of-mass energy of sqrt[s]=13  TeV. If observed, these rare processes would provide a unique test bench for the quantum chromodynamics factorization formalism used to calculate cross sections at colliders. Additionally, at future colliders, these decays could offer a new way to measure the W boson mass through fully reconstructed decay products.

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  • - The ATLAS experiment at the LHC conducted a search for long-lived particles (LLPs) using a large dataset (140 fb^{-1}) from proton-proton collisions at 13 TeV, focusing on LLPs with masses from 5 to 55 GeV that decay within the inner detector.
  • - The study considered scenarios where LLPs are produced from exotic Higgs boson decays and models involving axionlike particles (ALPs).
  • - No significant findings above expected background levels were detected, leading to the establishment of upper limits on various production rates involving the Higgs boson and the top quark related to LLPs and ALPs.
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  • The study investigates the associated production of Higgs and W bosons, focusing on how the relative signs of the Higgs couplings to W and Z bosons impact the process.
  • Two specific searches were conducted using large amounts of collision data from the LHC to analyze different coupling scenarios: one for opposite-sign couplings and another for same-sign (standard model-like) couplings.
  • The results significantly exclude the opposite-sign coupling hypothesis and set a strict upper limit on the production rate of this process compared to standard model predictions.
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  • Cushing's syndrome (CS) can be tricky to diagnose early, especially in patients with mild symptoms or mild autonomous cortisol secretion (MACS), making a timely diagnosis crucial for effective treatment and better outcomes.
  • In a study involving the German Cushing's registry, researchers analyzed 129 patients with CS and 48 with MACS to assess their clinical signs and comorbidities, finding that both groups had a significant number of health issues, mainly hypertension.
  • The study revealed that many patients with overt CS had only a few clinical signs at diagnosis, highlighting the variability in the symptoms and comorbidities among both CS and MACS patients.
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This Letter presents results from a combination of searches for Higgs boson pair production using 126-140  fb^{-1} of proton-proton collision data at sqrt[s]=13  TeV recorded with the ATLAS detector. At 95% confidence level (CL), the upper limit on the production rate is 2.9 times the standard model (SM) prediction, with an expected limit of 2.

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This Letter presents the first study of the energy dependence of diboson polarization fractions in WZ→ℓνℓ^{'}ℓ^{'}(ℓ,ℓ^{'}=e,μ) production. The dataset used corresponds to an integrated luminosity of 140  fb^{-1} of proton-proton collisions at a center-of-mass energy of 13 TeV recorded by the ATLAS detector. Two fiducial regions with an enhanced presence of events featuring two longitudinally polarized bosons are defined.

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  • Endogenous hypercortisolism shows different symptoms, and researchers are seeking to understand what factors influence its severity, especially focusing on the ABCB1 gene's role in glucocorticoid secretion.
  • The study examined 137 patients from the German Cushing's registry to see how the ABCB1 polymorphism rs2032582 affects steroid levels and clinical characteristics.
  • Results showed that patients with cortisol-producing adrenal adenomas who had the major allele GG of the ABCB1 polymorphism had higher cortisol levels and blood pressure compared to those with other genotype variations, suggesting the gene may influence disease severity.
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Sand flies, vectors capable of transmitting Leishmania spp. and causing leishmaniasis, have been a concern in the central region of Rio Grande do Sul, where canine leishmaniasis (CanL) has been documented since 1985. Notably, there has been a surge in CanL cases since 2017, with two autochthonous cases of human visceral leishmaniasis reported in the area in 2021.

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Statistical combinations of searches for charginos and neutralinos using various decay channels are performed using 139  fb^{-1} of pp collision data at sqrt[s]=13  TeV with the ATLAS detector at the Large Hadron Collider. Searches targeting pure-wino chargino pair production, pure-wino chargino-neutralino production, or Higgsino production decaying via standard model W, Z, or h bosons are combined to extend the mass reach to the produced supersymmetric particles by 30-100 GeV. The depth of the sensitivity of the original searches is also improved by the combinations, lowering the 95% C.

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  • Secondary hypogonadism (SH) is prevalent in men with Cushing's syndrome (CS) and mild autonomous cortisol secretion (MACS), significantly impacting testosterone levels.
  • In a study involving 30 men with CS and 17 with MACS, most had low testosterone levels, with improvements observed post-surgery.
  • Despite testosterone levels normalizing after treatment, some red blood cell parameters remained low, suggesting the need for further research.
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  • * The measurements utilized both semileptonic and hadronic decays of top quarks, along with events focused on single top quark production in the electroweak t channel.
  • * The combined result for the top quark mass is 172.52 GeV, with a reduced total uncertainty of 0.33 GeV, showcasing an improvement of 31% over previous measurements.
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  • Ultrafiltration technology effectively separates water from impurities but faces challenges due to the adsorption and aggregation of hydrophobic organic pollutants, leading to membrane degradation.* -
  • A new block amphiphilic polymer, PES-g-CMC@MWCNT, is developed by combining hydrophobic polyethersulfone and hydrophilic carboxymethyl chitosan, enhancing membrane stability by improving compatibility on surfaces.* -
  • The resulting ultrafiltration membranes show high water flux, good hydrophilicity, excellent antifouling properties, and impressive rejection rates for contaminants, indicating significant improvements in membrane function.*
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Lipids have essential functions as structural components of cellular membranes, as efficient energy storage molecules, and as precursors of signaling mediators. While deregulated glucose and amino acid metabolism in cancer have received substantial attention, the roles of lipids in the metabolic reprogramming of cancer cells are less well understood. However, since the first description of de novo fatty acid biosynthesis in cancer tissues almost 70 years ago, numerous studies have investigated the complex functions of altered lipid metabolism in cancer.

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  • Ferroptosis is a key form of cell death linked to various diseases, characterized by excessive peroxidation of fatty acids in cell membranes, which causes the cell to rupture.
  • This process is influenced by iron and redox balance within cells but can also be targeted for pharmacological treatments, making ferroptosis-related proteins potential candidates for new therapies.
  • A research consortium in Germany, along with leading experts, aims to review the mechanisms, significance, and methodologies related to ferroptosis to promote further research and potential new treatments for diseases affected by this process.
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A combination of searches for a new resonance decaying into a Higgs boson pair is presented, using up to 139  fb^{-1} of pp collision data at sqrt[s]=13  TeV recorded with the ATLAS detector at the LHC. The combination includes searches performed in three decay channels: bb[over ¯]bb[over ¯], bb[over ¯]τ^{+}τ^{-}, and bb[over ¯]γγ. No excess above the expected Standard Model background is observed and upper limits are set at the 95% confidence level on the production cross section of Higgs boson pairs originating from the decay of a narrow scalar resonance with mass in the range 251 GeV-5 TeV.

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Higgsinos with masses near the electroweak scale can solve the hierarchy problem and provide a dark matter candidate, while detecting them at the LHC remains challenging if their mass splitting is O(1  GeV). This Letter presents a novel search for nearly mass-degenerate Higgsinos in events with an energetic jet, missing transverse momentum, and a low-momentum track with a significant transverse impact parameter using 140  fb^{-1} of proton-proton collision data at sqrt[s]=13  TeV collected by the ATLAS experiment. For the first time since LEP, a range of mass splittings between the lightest charged and neutral Higgsinos from 0.

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Angular correlations between heavy quarks provide a unique probe of the quark-gluon plasma created in ultrarelativistic heavy-ion collisions. Results are presented of a measurement of the azimuthal angle correlations between muons originating from semileptonic decays of heavy quarks produced in 5.02 TeV Pb+Pb and pp collisions at the LHC.

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  • - Fryns syndrome (FS) is a genetic disorder involving various malformations, including congenital diaphragmatic hernia and central nervous system abnormalities.
  • - A study investigated a northern European family with two cases of FS: a boy who died at 2.5 months and a female fetus with similar developmental issues.
  • - Genetic analysis identified two mutations affecting RNA splicing as the cause of FS in these patients, confirming the genetic basis of the syndrome.
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Background: Normalization of hypercortisolism is essential to reduce morbidity and mortality in patients with Cushing's syndrome (CS). The aim of this analysis was to assess biochemical control rates in patients with Cushing's disease (CD), ectopic Cushing's syndrome (ECS) and adrenal Cushing's syndrome (ACS).

Methods: Patients with confirmed CS (n= 296) treated in a single tertiary care center were retrospectively analysed (185 CD, 27 ECS, 84 uni- and bilateral ACS).

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