Publications by authors named "Vnukova Z"

One of the global problems today is energy-its production and distribution. As the human population grows, the consumption of energy rises simultaneously. However, the natural sources are limited, and so the focus on power savings becomes more and more important.

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Patches of autoskin (0.5 x 1.0 mm) were grafted on a full-thickness rat back skin wound (5.

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On the basis of experimental and clinical investigations the authors have shown that extensive burns in patients with true deficiency of donor resources might be treated by the method of micro-transplantation of the skin which consists in plasty of the wounds by pieces of auto-skin of small size. The reduction of size of the skin pieces gives the enlargement of the total line of marginal epithelialization and great plasty coefficient as compared with traditional methods of surgical treatment.

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Experiments with rats of different ages have established the potential of microautotransplants (MATR) of skin (0.5-3.0 mm2 in size) to produce neoepidermis on fresh and granulating wounds.

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It's experimentally show na 40-fold expansion of deep and wide skin wound covering by microtransplantation. For all this it is determined that quantitative and qualitative parameters of neoskin didn't depend on skin microfragments concentration 0.5 X 1.

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A new technique of wide wound skin epithelialization by free transplantation of autologous skin fragments 1 mm2 in size is demonstrated. The experiments were carried out on strainless rats of different age, 100 per cent epithelialization of wound 5 mm2 in grafting skin micro-autotransplantation (MATR) was observed. The primary effectiveness of wound closing square to MATR square was 1:20.

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During 35-day hypokinesia rat spongy bone in the tibia and vertebrae varied in two phases. The first phase (up to 15 days) was induced by a stress-reaction and the second phase by adaptation to hypokinesia. Under the influence of subcutaneous injections of hydroxydimethyl aminopropylidene biphosphonate (AMOK) at a dose of 0.

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Oral administration of hydroxy-dimethyl aminopropylene biphosphonate (DMAP) at a dose of 0.5 mg/kg increased the volume density (mass) of trabecular bone in the tibial metaphysis of untreated rats and helped to maintain it at the normal level in hypokinetic rats. Oral administration of hydroxy-ethylidene biphosphonate (OEDP) at a dose of 20 mg/kg and vitamin 24,25(OH)2D3 at a dose of 1,25 micrograms did not induce any quantitative changes in bones of untreated or immobilized rats.

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The diphosphonate effect on bones was studied in Wistar male rats weighing about 200 g. The rats were kept for 60 days in small-size cages where their motor activity was diminished. Every day the rats were given per os 0.

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Examination of spongy bones of rats exposed to clino- and antiorthostatic hypokinesia showed that changes in bone mass, bone cells and their precursors were similar in both cases. The bone resorption-bone formation process remained balanced. However, bone responses clino- and antiorthostatic hypokinesia exhibited certain differences.

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The experiments were carried out on Wistar SPF rats that were immobilized for 35 days. By heterotopic marrow cell transplantation under the kidney capsule to the normal rats and by cloning these cells in vitro it was found that osteogenetic potentials were significantly inhibited and the amount of osteogenetic precursor cells was reduced. The addition of 24,25(OH)2D3 vitamin (at a dose of 1.

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On total preparations of the cornea of rats flown on Cosmos-936 and Cosmos-1129 the following parameters of the epithelial mitosis were studied: mitotic index, ratio of mitotic phases, number of abnormalities of cell division, and number of chromosome aberrations in anaphases. These parameters were considered to be indicators of physiological regeneration. The nuclear volume of cells of two inner epithelial layers was measured, using a modified karyometric technique that yielded representative data.

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The effect of a constant magnetic field of 1000 and 3000 oersted on mammalian cell cultures was examined. The effect of prolonged (12 days with three successive subcultures) and short-term intermittent action (repeated 6 times 60 min exposures with a 60 min interval) was studied. The magnetic effect was evaluated with respect to variations in the cell population density, mitotic activity and cytogenetic parameters.

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