[Psychopathology of depressive-delusional states with religious content].

Objective: Identification of psychopathological characteristics of depressive-delusional states with religious content, development of a typology, determination of formation features, nosological assessment.

Material And Methods: A total of 79 patients (47 female, 32 male, mean age 27±6.5 years) with depressive-delusional states with religious content within the affective and schizophrenia spectrum disorders were studied.

X-ray dynamical diffraction by quasi-monolayer graphene.

We study the processes of dynamical diffraction of the plane X-ray waves on the graphene film/SiC substrate system in the case of the Bragg diffraction geometry. The statistical dynamical theory of X-ray diffraction in imperfect crystals is applied to the case of real quasi-two-dimensional systems. The necessity of the taking into account of the variability of the lattice parameter of multilayer graphene, as well as the influence of thickness on the thermal Debye-Waller factor at the calculation of the complex structural factors and Fourier components of polarizability, is demonstrated.

Comparative study of quality of life 9 months post-COVID-19 infection with SARS-CoV-2 of varying degrees of severity: impact of hospitalization vs. outpatient treatment.

Purpose: This experimental study was conducted during the post-COVID-19 period to investigate the relationship between the quality of life 9 months after and the severity of the SARS-CoV-2 infection in two scenarios: hospitalization (with/without medical oxygen) and outpatient treatment.

Methods: We employed the EQ-5D-5L Quality of Life tests and the PSQI as a survey to evaluate respondents' quality of life 9 months after a previous SARS-CoV-2 infection of varying severity.

Results: We identified a clear difference in the quality of life of respondents, as measured on the 100-point scale of the EQ-5D-5L test, which was significantly lower 9 months after a previous SARS-CoV-2 infection for Group 1 ( = 14), respondents who had received medical attention for SARS-CoV-2 infection in a hospital with oxygen treatment, compared to those with the SARS-CoV-2 infection who were treated without oxygen treatment (Group 2) ( = 12) and those who were treated on an outpatient basis (Group 3) ( = 13) (H = 7.

[The effectiveness of auditory training using virtual reality technologies in persons with chronic sensorineural hearing loss].

Objective: To study the effectiveness of auditory training using virtual reality technologies in people with chronic sensorineural hearing loss in dynamics.

Material And Methods: The study included 68 patients aged from 24 to 97 years (mean age 57.63±15.

[Features of tinnitus in older patients with autonomic dysfunction].

Objective: To establish the features of tinnitus in older age patients with autonomic dysfunction.

Material And Methods: We examined 94 patients aged 60 to 93 years (average age is 75.4±3.

[The results of auditory training in virtual reality in patients of older age groups.].

The increase in life expectancy of the population is reflected both in statistics on chronic sensorineural hearing loss and on issues related to hearing rehabilitation methods. Evaluation of the effectiveness of the use of auditory training using the virtual reality program developed by us in patients of older age groups as an additional method of rehabilitation was carried out. 68 patients took part in the study (average age was 81,3±2,1 years), according to the results of the training, the parameters of speech and spatial hearing were evaluated.

[Mobile solutions in hearing assessment].

Purpose Of The Study: To evaluate the effectiveness of the application of the web application "Automated system of primary hearing assessment" created by us for the diagnosis of hearing impairment in different age groups.

Material And Methods: With the help of this web application, 712 patients were examined in 3 age groups: group 1 - patients aged 18 to 44 years, 196 people (average age 25.6±2.

[Speech and spatial characteristics of hearing in older age groups using virtual reality technologies].

Spatial and speech characteristics of hearing are needed to monitor the rehabilitation of sensorineural hearing loss in patients of older age groups. Using the created «Program for the assessment of speech, spatial and qualitative characteristics of hearing using virtual reality» increases the level of hearing diagnostics using a computerized audiovisual script. The purpose of the study is a comparative analysis of the speech, spatial and qualitative characteristics of hearing before and after using virtual reality in patients of older age groups.

[Resolution of the Council of Experts «Bioregulatory drugs in the complex treatment of common ENT diseases»].

Within the framework of the III All-Russian scientific and practical conference of otorhinolaryngologists, audiologists, somnologists and maxillofacial surgeons with international participation, a meeting of experts in the field of ENT diseases was held with the support of Heel RUS LLC, October 17-18, 2019, Kazan.

[Applicability of antibacterial agents in chronic tonsillitis treatment].

The purpose of the present study was to evaluate the effectiveness of nitrofuranes applied for the treatment of chronic tonsillitis. A total of 92 subjects divided into three cohorts were involved in this study. Cohort 1 included 43 patients presenting with decompensated chronic tonsillitis and having pathogens in palatine tonsil lacunae.

Effect of the age of pregnant females on brain development in the offspring.

We examined offspring of 9-10 and 3.5-4 month-old female rats. Female offspring (14, 21, 28, 35, and 40 days) of old rats had higher body weight than offspring of young animals.

[The role of group psychotherapy in combined modality therapy of juvenile endogenous depression].

The paper presents the study in of the combined psychopharmaco-psychocorrective method designed specially for juvenile patients with endogenic depressive disorders. Psychocorrective measures included the method of "rehabilitation training of social habits" used on the stage of hospital therapy and psychocorrective training according to "social support" method used in group psychotherapy outpatiently. A 5 year follow-up study performed in 110 showed that psychotherapy has increased efficiency of the therapy in terms of both reduction of clinic disorders in the acute period and prophylaxis of the relapses as well as social readaptation.

[The use of betaserk in patients with cochlear-vestibular disorders].

20-year experience with 220 cases of cochleovestibular disorders treated with betaserk shows high efficacy of this drug in the above patients, especially at initial stages of Meniere's disease. Betaserk is recommended for wide outpatient practice.

Abnormal recognition of facial expression of emotions in depressed patients with major depression disorder and schizotypal personality disorder.

The aim of this paper is to study the recognition of facial expression of emotions in depressed patients with major depressive disorder (MD) and schizotypal personality disorder (STP). The pictures of sad, emotionally neutral, and happy faces followed by a masking stimulus were displayed for 80 msec on a computer screen randomly in the left or right hemifield of vision (LHF and RHF). The subjects had to respond by pressing a three position key.

[The functional activity of the lymphocyte subpopulations in patients with schizophrenia and schizoaffective psychosis].

The functional activity of natural killer (NK) and of T-helper (TH) lymphocytes was examined both in 19 patients with schizophrenia and in 6 patients with schizoaffective psychosis as well as in 93 control individuals. The patients were examined both before the treatment and two months after it. The cytotoxic level of NK lymphocytes was considerably decreased in all the patients before the treatment.

[The clinical evaluation of the antidepressive activity of fluoxetine].

The authors studied therapeutic properties of fluoxetine in the treatment of 100 patients with endogenous depressions. The drug was introduced during 6 weeks in a daily dose 20 mg. On the basis of the analysis of its clinical action and adverse reactions, fluoxetine belonging to the class of antidepressants has been ascertained.

[The recognition of the facial expression of emotions by patients with endogenous depression (clinico-psychophysiological research)].

The recognition of facial emotional expression in depressed patients with major depressive disorder (MDD) and slow progressive schizophrenia (SPS) in acute state and in remission was studied in comparison with healthy persons. All the subjects were right-handed. The drawings of sad, neutral and happy faces followed by masking stimulus were displayed in the center field and in the left or right hemifield of vision on the computer screen for 80 ms.

[Sacral epidural anesthesia as a method in technically complicated abortions].

An experience is reported with the use of epidural-sacral anesthesia for artificial abortion in 102 primiparae+- and nulligravidas and in 86 patients with scarring deformity or partial atresia of the endocervix. Two percent trimecaine was used in a single dose 6 mg/kg. A high efficiency of anesthesia was seen in 92% of cases.

[Nonspecific resistance of the body in patients with peptic ulcer and chronic gastritis].

Indices of unspecific resistance (bactericidal serum activity, phagocytic reaction of neutrophils, lysozyme) were examined in 128 patients with ulcer disease and chronic gastritis. Changes of local and general mechanisms of unspecific reactivity of the gastro-intestinal tract result not only in disorders of the defence system but also in a reduction of viability of the gastric and duodenal epithelium with development of alteration processes. In this condition bacterial and protein antigens may change the immunological status of the body.

[Lipid peroxidation processes in patients with schizophrenia].

In schizophrenic patients, the course of lipid peroxidation (LP) was investigated as indicated by pentane contents in the expired air (gas chromatography) during a course of psychotropic drug therapy. In 80% of the patients LP was activated before the therapy and reduced in its course with the levels in remission comparable to those characteristic of healthy controls. The LP decreased in a "leap-like" manner with episodes far exceeding the control levels.

[Prognosis of a favorable outcome in juvenile slowly progressing neurosis-like schizophrenia based on catamnestic data].

On the basis of the results of an 18-26-year-long follow up of 100 patients with juvenile slowly progressive neurosis-like schizophrenia with an onset of the disease in youth the authors have identified a group of patients (n = 25) who presented practical cure. Comparison of the peculiarities of neurosis-like disturbances and their dynamics during the active stage of the disease in this group and in patients in whom stable neurosis-like manifestations persisted up to the late stages of the disease (n = 75) has made it possible to determine those types of neurosis-like states which correlate with the outcome of the disease. Some clinical and pathogenetic signs have been identified which help specify some aspects of the clinical and social prognosis.

[Characteristics of the organization of the psychosocial and vocational rehabilitation of patients with juvenile schizophrenia (a clinico-psychological study of the slowly progressing form with a favorable outcome)].

Clinical catamnestic and experimental psychologic techniques allowed the authors to single out a range of personality and psychosocial structures in patients with juvenile slow progredient neurosis-like schizophrenia with favorable outcome up to "virtual recovery". Influencing these structures with respect to the patients' age could promote their general and special activities, heighten their level and quality of adaptation to major spheres of social functioning. This provided a basis for establishing the major goals of social rehabilitative and psychic corrective aid to the juvenile patients.