Mathematical model explains differences in Omicron and Delta SARS-CoV-2 dynamics in Caco-2 and Calu-3 cells.

Within-host infection dynamics of Omicron dramatically differs from previous variants of SARS-CoV-2. However, little is still known about which parameters of virus-cell interplay contribute to the observed attenuated replication and pathogenicity of Omicron. Mathematical models, often expressed as systems of differential equations, are frequently employed to study the infection dynamics of various viruses.

Development of a novel mathematical model that explains SARS-CoV-2 infection dynamics in Caco-2 cells.

Mathematical modeling is widely used to study within-host viral dynamics. However, to the best of our knowledge, for the case of SARS-CoV-2 such analyses were mainly conducted with the use of viral load data and for the wild type (WT) variant of the virus. In addition, only few studies analyzed models for data, which are less noisy and more reproducible.

Instrumental tactile diagnostics in robot-assisted surgery.

Background: Robotic surgery has gained wide acceptance due to minimizing trauma in patients. However, the lack of tactile feedback is an essential limiting factor for the further expansion. In robotic surgery, feedback related to touch is currently kinesthetic, and it is mainly aimed at the minimization of force applied to tissues and organs.

Automated Detection of Heterogeneity in Medical Tactile Images.

Artificial tactile sensing is a capability important for many applications and, in particular, for endoscopic surgery. A recently developed Medical Tactile Endosurgical Complex (MTEC) that is a certified and commercially available product is an efficient tool that provides such a capability. Currently the analysis of intraoperative tactile images that are registered and visualized by MTEC is performed manually by a surgeon.