Publications by authors named "Vladimir Spasojevic"
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Synopsis of recent research by authors named "Vladimir Spasojevic"
- Vladimir Spasojevic's research primarily focuses on improving the stability and efficacy of therapeutic antibodies, utilizing innovative engineering techniques and understanding the impact of excipients in protein formulations for biopharmaceutical applications.
- His studies have explored how isotonic concentrations of excipients affect the dimerization rates of antibodies during refrigerated storage, emphasizing the need for informed excipient selection during the early stages of drug development.
- Spasojevic has developed methods for generating high-affinity humanized antibodies without the use of hybridomas, highlighting the potential of mammalian cell display and somatic hypermutation to streamline antibody production and enhance stability.
