Publications by authors named "Vladimir Rosenov Koynarev"
The formation of phase separated membrane domains is believed to be essential for the function of the cell. The precise composition and physical properties of lipid bilayer domains play crucial roles in regulating protein activity and governing cellular processes. Perturbation of the domain structure in human cells can be related to neurodegenerative diseases and cancer.
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- Poly-proline II helices are special shapes found in proteins that help them interact with other molecules, making them flexible and often misinterpreted.
- Scientists discovered that a protein called YadA from a germ called Yersinia enterocolitica has a poly-proline II helix that helps it stick to a substance called heparin.
- The YadA protein needs specific parts to connect with heparin, and if host cells can’t produce heparin properly, they aren’t affected by YadA, which may help the germ cause disease in certain situations.