Intraoperative Bleeding Control with Terlipressin in Functional Endoscopic Sinus Surgery.

Objective: To evaluate the use of terlipressin for intraoperative bleeding reduction in functional endoscopic sinus surgery (FESS).

Methods: This prospective, randomized, single-center, single-blinded cohort study included 74 cases of FESS performed under general anesthesia (GA). The patients were randomized into two groups: WT (without terlipressin, n = 39) and T (with 200 μg terlipressin, n = 35).

O-antigen modulates infection-induced pain states.

The molecular initiators of infection-associated pain are not understood. We recently found that uropathogenic E. coli (UPEC) elicited acute pelvic pain in murine urinary tract infection (UTI).

Gender specific pelvic pain severity in neurogenic cystitis.

Purpose: Interstitial cystitis/painful bladder syndrome is a chronic bladder inflammatory disease of unknown etiology that is often regarded as neurogenic cystitis. The condition is associated with focal inflammation, urothelial lesions, voiding dysfunction and pain in the pelvic/perineal area. Approximately 90% of patients with the condition are women, suggesting the possibility of hormonal involvement in interstitial cystitis/painful bladder syndrome symptoms.

PTP1B deficiency exacerbates inflammation and accelerates leukocyte trafficking in vivo.

It is reported that PTP1B limits cytokine signaling in vitro. However, PTP1B's function during inflammation in vivo is not known. In this report, we determined whether PTP1B deficiency affects allergic inflammation in vivo.

Host-pathogen interactions mediating pain of urinary tract infection.

Background: Pelvic pain is a major component of the morbidity associated with urinary tract infection (UTI), yet the molecular mechanisms underlying UTI-induced pain remain unknown. UTI pain mechanisms probably contrast with the clinical condition of asymptomatic bacteriuria (ASB), characterized by significant bacterial loads without lack symptoms.

Methods: A murine UTI model was used to compare pelvic pain behavior elicited by infection with uropathogenic Escherichia coli strain NU14 and ASB strain 83972.

Environmental mapping based on spatial variability.

Environmental maps show the probable environmental states of different types of land use or development of landscape in a geographic context. Remotely sensed data are particularly efficient for environmental mapping in order to outline major environmental types. Multiple schemes of image classification used in environmental mapping are either traditionally statistical or heuristic.