Dyslipidemia in pediatrician's practice.

Atherosclerosis ranks first among cardiovascular system diseases. It is the "disease of the century", and more than 50% of people with circulatory pathology die of it. The clinical manifestation of atherosclerosis is observed at the middle and older ages, but it is known that the pathological process develops much earlier.

Cardiorespiratory synchronism in estimation of regulatory and adaptive organism status.

The proposed method of quantitative estimation of regulatory and adaptive status (RAS) of human organism is based on complex responses of two major vegetative functions - breath and heart rates under organism exposure to a number of factors and diseases. It has been evidenced that during the follicular menstruation stage and during optimum readiness of female organism for childbirth RAS increases, however, stress impact can also cause RAS set off to decrease. Likewise, the possibility of quantitative organism stress resistance estimation is also presented.

On the conscious control of the human heart.

This study describes methods of volitional management of heart rhythms and proves that it is possible by means of management of its operations, subject to arbitrary control, which also has a strong functional connection to the center of the heart rhythm formation in the brain. Experiments demonstrate that it is possible for arbitrary changes in the heart rhythm to be made through conscious control of the breathing rhythm, and even a short-term cardiac arrest by means of contracting abdominal muscles. We postulate that the management of human heart rhythm is indirectly regulated through arbitrary controlled operations.

Interaction of brain and intracardiac levels of rhythmogenesis hierarchical system at heart rhythm formation.

A single-stage bilateral conduction blockade of the vagus nerves (functional denervation) by constant anodal current was carried out in 13 dogs which are under anesthesia and 3-5 days after operation in chronic experiments. In anesthetized animals, "functional denervation" led to acceleration of the heart rhythm from 102.4+/-3.

Alternative view on the mechanism of cardiac rhythmogenesis.

Background: This article advances an hypothesis that there is duplication of the heart rhythmogenesis system.

Methods And Results: The following article reviews available data and advances an hypothesis to suggest new ideas about the mechanisms of cardiac rhythm generation. The hypothesis is that along with the existence of an intracardiac pacemaker, the generator of cardiac rhythm exists in the central nervous system - in the efferent structures of the cardiac centre of the medulla oblongata.

Hierarchy of the heart rhythmogenesis levels is a factor in increasing the reliability of cardiac activity.

Along with the existence of an intracardiac pacemaker a generator of cardiac rhythm exists in the central nervous system - in the efferent structures of the cardiovascular center of the medullar oblongata. Neural signals originating there in the form of bursts of impulses conduct to the heart along the vagus nerves and after interaction with cardiac pacemaker structures cause generation of the cardiac pulse in exact accordance with the frequency of the neural bursts. That the intrinsic cardiac rhythm generator is a life-sustaining factor that maintains the heart pumping function when the central nervous system is in a stage of deep inhibition.

Integration of the heart rhythmogenesis levels: heart rhythm generator in the brain.

We propose that along with the intracardiac pacemaker, a generator of cardiac rhythm exists in the central nervous system--in the efferent structures of the cardiovascular center of the medullar oblongata. Signals in the medulla oblongata arise as a result of the hierarchic interaction of the brain structures. Neural signals originating there in the form of bursts of impulses conduct to the heart along the vagus nerves and after interaction with cardiac pacemaker structures, cause generation of the cardiac pulse in exact accordance with the frequency of "neural bursts".