New benzoquinone pigments from the hydnoid fungus and their biosynthetic relationship.

Chemical investigation of the hydnoid fungus resulted in the isolation of five compounds, including two new sarcodontic acid derivatives - setosic acid () and 7,8-dehydrohomosarcodontic acid () along with three known benzoquinone pigments - sarcodontic acid (), 4,5-dehydrosarcodontic acid () and dihydrosarcodontic acid (). The structures were elucidated using spectroscopic methods (UV, NMR and HR-ESIMS). The biosynthetic relationship of the isolated compounds is proposed and discussed.

Isolation and Characterization of a New Flavone C-glycoside Isoembinin from Iris lacteal along with its Effects on Platelet Activation.

One new compound isoembinin 1 along with ten known compounds 2-11 were isolated from the terrestrial parts of Iris lactea Pall. All of the compound structures were determined through extensive 1D and 2D NMR experiments along with HR-ESIMS analysis and comparison with literature data. Because many flavonoids exert antiplatelet and antioxidant activity we tested the effects of the isolated flavone C-glycosides 1-9 on platelet activation and reactive oxygen species (ROS) production.

New cyclic diarylheptanoids from the false heartwood of Ehrh.

Two undescribed (- and five known cyclic diarylheptanoids (-) were isolated from the false heartwood of white birch ( Ehrh.). All structures were elucidated through extensive 1D and 2D NMR experiments and HR-ESI-MS data, along with comparison of their spectroscopic data with those reported in the literature.

Effect of Phytopreparations Based on Bioreactor-Grown Cell Biomass of , and on Carbohydrate and Lipid Metabolism in Type 2 Diabetes Mellitus.

In the present study, we explored the therapeutic potential of bioreactor-grown cell cultures of the medicinal plant species , and to treat carbohydrate metabolism disorders (CMDs) in laboratory rats. In the adrenaline model of hyperglycemia, aqueous suspensions of cell biomass pre-administered at a dose of 100 mg dry biomass/kg significantly reduced glucose level in animal blood 1-2.5 h ( and ) or 1 h () after adrenaline hydrochloride administration.

Medical Species Used in Russia for the Management of Diabetes and Related Disorders.

Polyherbal mixtures called "medical species" are part of traditional and officinal medicine in Russia. This review aimed to analyze medical species used in Russia for the treatment of diabetes and related disorders. The information relevant to medical species, diabetes, and obesity was collected from local libraries, the online service E-library.

A new dimethoxy dihydrochalcone isolated from the shoots of L.

A new dihydrochalcone, 2',4'-dimethoxydihydrochalcone (), together with 7 known compounds, 2',4'-dihydroxydihydrochalcone (), 2'-hydroxy-4'-methoxydihydrochalcone (), 2'-hydroxy-4'-methoxychalcone (), 1-(3,5-dihydroxy-4-methoxyphenyl)-2-(3-hydroxyphenyl) ethane (), 2,3,4,7-tetramethoxy-9,10-dihydrophenanthrene (), 5-hydroxy-2,3,4-trimethoxy-9,10-dihydrophenanthrene () and 5,7-dihydroxy-6,8-dimethyl flavanone () were isolated from the shoots of L. The structures of these compounds were elucidated using 1D and 2D NMR experiments along with HR-ESI-MS. Compound is reported for the genus for the first time.

Medicinal plants from the 14 edition of the Russian Pharmacopoeia, recent updates.

Ethnopharmacological Relevance: Herbal medicine in Russia has a long history starting with handwritten herbalist manuscripts from the Middle Ages to the officinal Pharmacopoeia of the 21st century. The "herbophilious" Russian population has accumulated a lot of knowledge about the beneficial effects of local medicinal plants. Yet, for a long time, Russian traditional and officinal herbal medicine was not well known to the international audience.

Antihypoxic Action of Panax Japonicus, Tribulus Terrestris and Dioscorea Deltoidea Cell Cultures: In Silico and Animal Studies.

Chemical diversity of secondary metabolites provides a considerable variety of pharmacological actions with a significant extension due to their combinations in plant extracts. Production of plant-derived medicinal products in cell cultures has advantages because of the efficient use of different biotic and abiotic elicitors and better control of the developmental processes. Using PASS software, we predicted biological activity spectra for phytoconstituents identified in cell cultures of Panax japonicus (12 molecules), Tribulus terrestris (4 molecules), and Dioscorea deltoidea (3 molecules).