Multifunctional tunable ZnFeO@MnFeO nanoparticles for dual-mode MRI and combined magnetic hyperthermia with radiotherapy treatment.

With the increase in non-communicable diseases, cancer is becoming one of the most lethal ailments of the coming decades. Significant progress has been made in the development of NPs that combine diagnostic and therapeutic properties in a single system. Multimodal NPs that sequentially perform MRI diagnostics with increased contrast and then act as synergistic agents for magnetic hyperthermia and radiotherapy can be considered as next-generation anticancer drugs.

Magnetically guided capsule endoscopy.

Wireless capsule endoscopy (WCE) is a powerful tool for medical screening and diagnosis, where a small capsule is swallowed and moved by means of natural peristalsis and gravity through the human gastrointestinal (GI) tract. The camera-integrated capsule allows for visualization of the small intestine, a region which was previously inaccessible to classical flexible endoscopy. As a diagnostic tool, it allows to localize the sources of bleedings in the middle part of the gastrointestinal tract and to identify diseases, such as inflammatory bowel disease (Crohn's disease), polyposis syndrome, and tumors.

Developing Antitumor Magnetic Hyperthermia: Principles, Materials and Devices.

Background And Objective: Methods of local or loco-regional anticancer treatment are of the utmost importance because the therapeutic 'power' is applied directly to the disease site. Consequently, general toxicity is minimized. Hyperthermia, that is, a sustained increase of intratumoral temperature up to 45oC, has been investigated as a perspective treatment modality alone and/or in combination with ionizing radiation or chemotherapy.