Publications by authors named "Vladimir Dytrych"
Article Synopsis
- * This study aimed to explore long-term pulmonary perfusion issues in COVID-19 survivors who experienced severe acute respiratory distress syndrome (ARDS) and were treated with ECMO at a specific institution.
- * Out of 80 patients who survived ECMO treatment, only 37 were analyzed; while VTE occurred frequently during acute illness, no ongoing pulmonary perfusion abnormalities were found after an average of 14 months post-ECMO.
Article Synopsis
- Supraventricular tachycardia (SVT), a common issue for patients with pulmonary hypertension (PH), includes conditions like atrial fibrillation and atrial flutter, which can worsen heart function.
- Restoring normal heart rhythm through methods like catheter ablation can lead to improvements, though long-term success is challenged by the potential for arrhythmia recurrence.
- Catheter ablation is generally effective for less complex SVTs, but its use for complex cases like atrial fibrillation needs to be more tailored due to higher risks and varying outcomes.
Article Synopsis
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- The error may impact the interpretation of data or findings presented in the document. !*
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Aims: Atrial fibrillation (AF), typical atrial flutter (AFL), and other atrial tachycardias (ATs) are common in patients with pulmonary hypertension. Frequently, several supraventricular arrhythmias are successively observed in individual patients. We investigated the hypothesis of whether more extensive radiofrequency catheter ablation of the bi-atrial arrhythmogenic substrate instead of clinical arrhythmia ablation alone results in superior clinical outcomes in patients with pulmonary arterial hypertension (PH) and supraventricular arrhythmias.
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- This analysis explored how hospitalizations impact the survival of patients with chronic thromboembolic pulmonary hypertension (CTEPH) in the Czech Republic, focusing on data from 2003 to 2016.
- It found that a first hospitalization due to CTEPH is a significant predictor of increased mortality, especially in patients who are not eligible for pulmonary endarterectomy (PEA), showing nearly double the risk of death.
- The study suggests that inoperable CTEPH patients may benefit from additional medical or interventional treatments based on their hospitalization history.
Article Synopsis
- This study analyzed the occurrence and survival rates of chronic thromboembolic pulmonary hypertension (CTEPH) in the Czech Republic from 2003 to 2016, focusing on patients who were treated with pulmonary endarterectomy (PEA).
- Out of 453 patients diagnosed, about 52.1% had PEA surgery, but 34.1% of those still suffered from residual pulmonary hypertension afterward.
- The findings showed a CTEPH incidence rate of 4.47 patients per million per year, with an overall median survival of 11.2 years after diagnosis, highlighting significant differences in survival between operated patients and those who did not undergo surgery.
Article Synopsis
- Balloon pulmonary angioplasty (BPA) is a new treatment for chronic thromboembolic pulmonary hypertension (CTEPH) patients who can't undergo pulmonary endarterectomy (PEA) or have ongoing high blood pressure after the procedure.
- A study evaluating 160 BPA procedures in 64 patients at a Czech referral center showed significant improvements in various health metrics, including heart function and exercise capacity, in a subgroup of 25 patients who completed the treatment series.
- The procedure had a low complication rate, with only one fatal event and 19 non-fatal issues, primarily hemoptysis, while the overall survival rate at 12 months was high at 94.6%.
The impact of riociguat on clinical parameters and quality of life in patients with chronic thromboembolic pulmonary hypertension - results of a retrospective clinical registry.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
June 2021
Article Synopsis
- The registry aimed to evaluate the effects of riociguat on clinical outcomes and quality of life in patients with chronic thromboembolic pulmonary hypertension (CTEPH) who could not undergo surgery or had surgery that did not fully resolve their condition.
- The study collected retrospective data from 51 patients over a period of approximately 5 months and 1 year after starting riociguat, noting improvements in walking distance, quality of life scores, and self-assessment of health status.
- Results showed significant health improvements and good tolerability for riociguat, with an 89.1% annual survival rate, indicating its effectiveness in real-world clinical settings.
Acute pulmonary embolism (PE) bears a significant burden on health and survival. Rapid and accurate risk stratification and management are of paramount importance to ensure the highest quality of care. This present article summarizes currently available and emerging management strategies for the disease.
View Article and Find Full Text PDFPulmonary embolism is an important clinical entity with considerable mortality despite advances in diagnosis and treatment. In the present article, the authors offer a comprehensive review focused mainly on epidemiology, risk factors, risk stratification, pathophysiological considerations and clinical presentation. Diagnosis based on assessment of clinical likelihood, electrocardiography, chest x-ray, D-dimer levels, markers of myocardial injury and overload, and blood gases is discussed in detail.
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- Mitochondrial disorders are a diverse group of diseases that can affect multiple body systems, particularly the heart (myocardium), often resulting in severe symptoms starting in infancy or childhood.
- Most mitochondrial cardiomyopathy cases are linked to other conditions like myopathy and encephalopathy, with a high mortality rate in early life.
- The case described involves a 35-year-old male diagnosed with hypertrophic cardiomyopathy due to a specific mitochondrial DNA mutation, presenting initially with a stroke but without other signs of mitochondrial disease.
Long-term prognostic impact of hyponatremia in the ST-elevation myocardial infarction.
Scand J Clin Lab Invest
February 2011
Article Synopsis
- The study examined how low sodium levels (hyponatremia) during the early phase of ST elevation myocardial infarction (STEMI) affected patient outcomes and long-term survival.
- Out of 218 patients with acute STEMI, 33% experienced hyponatremia, which was linked to more severe heart issues and a greater risk of complications like cardiogenic shock and renal failure.
- Results showed that hyponatremic patients had significantly lower long-term survival rates compared to those with normal sodium levels, highlighting the importance of monitoring sodium during treatment.
Article Synopsis
- A young male with HIV myocarditis experienced sudden cardiac death due to a dangerous heart rhythm, which is not commonly documented in medical literature.
- The case highlights the need to consider HIV myocarditis as a potential cause of serious heart issues, including malignant ventricular arrhythmias and sudden cardiac death.
- This situation emphasizes the importance of understanding the link between HIV and heart health, especially in young patients.
Article Synopsis
- - The study examined the effects of biphasic (BP) and monophasic (MP) electrical cardioversion on serum cardiac markers in patients with supraventricular tachyarrhythmia (SVT).
- - Results showed that higher cumulative energy (CE >150J) during MP cardioversion resulted in significant elevations of creatine kinase (CK) and myoglobin, while BP cardioversion led to smaller increases in CK but similar myoglobin levels.
- - Overall, the study concluded that electrical cardioversion does not indicate myocardial injury, with CK and myoglobin increases likely due to skeletal muscle damage, particularly more pronounced in MP cardioversion.