The Role of Inflammatory and Hemostatic Markers in the Prediction of Severe Acute Pancreatitis: An Observational Cohort Study.

Introduction: Acute pancreatitis (AP) is a serious inflammatory disease of the pancreas that can lead to significant morbidity and increased mortality. The special role of inflammation and disruption of the hemostatic system in the development of severe forms of the disease is known, however, the relationship between inflammatory and anti-inflammatory cytokines and thromboelastogram parameters has not been sufficiently studied.

Aim: The aim of this study is to assess the prognostic significance of thromboelastogram parameters, interleukin-6, and interleukin-22 levels in assessing the risk for developing severe forms of acute pancreatitis.

Comparative pre- and postoperative results analysis of functional state of the esophagus assessment in patients with various stages of achalasia.

Objective: The aim of this study was to evaluate main results of morpho-functional state of the esophagus assessment in patients with various stages of achalasia before and after surgical treatment.

Methods: Between 1993 and 2002, a total of 65 patients with achalasia (26 males, 39 females; mean age 44.5+/-14.